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Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:

2025 05

Page:

843-849

Research Field:

Publishing date:

Info

Title:

Research progress of function of zinc finger protein ZC3H15 and its role in tumour

Author(s):

CHEN Xingzhao; YAN Wen

Cancer Center,the Affiliated Guangdong Second Provincial General Hospital of Jinan University,Guangdong Guangzhou 510317£¬China.

Keywords:

zinc finger protein; ZC3H15; malignant tumor

PACS:

R730

DOI:

10.3969/j.issn.1672-4992.2025.05.019

Abstract:

ZC3H15 is a member of the CCCH-type zinc finger protein family.This protein plays an important role in cell proliferation,apoptosis,cell adhesion and transcription processes.Recent studies have shown that ZC3H15 is closely related to the development and progression of many tumors.Multiple studies have shown its abnormal expression in various malignant tumors such as hepatocellular carcinoma,gastric cancer,lung cancer,glioblastoma and acute myeloid leukemia,affecting patient prognosis and survival.With the deepening of research,the role and mechanism of ZC3H15 in malignant tumors are gradually being revealed.This paper aims to elaborate on the structural features,biological functions,roles in malignant tumors and mechanisms of ZC3H15 protein,summarize the latest research progress,in order to provide help for the prevention and treatment of tumors.

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Memo

Memo:

National Natural Science Foundation of China(No.81302965);¹ú¼Ò×ÔÈ»¿Æѧ»ù½ð£¨±àºÅ£º81302965£©£»¹ã¶«Ê¡»ù´¡ÓëÓ¦Óûù´¡Ñо¿»ù½ðÏîÄ¿£¨±àºÅ£º2020A1515010182£©

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