|Table of Contents|

Research progress of moesin in tumor development,diagnosis and treatment

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2025 03
Page:
473-478
Research Field:
Publishing date:

Info

Title:
Research progress of moesin in tumor development,diagnosis and treatment
Author(s):
SUN Yuanyuan; ZHANG Zhongyu; ZHANG Yanyan; YANG Jiamei
Department of Oncology,the Second Affiliated Hospital of Zhengzhou University,Henan Zhengzhou 450000，China.
Keywords:
moesin; tumor; treatment; research progress
PACS:
R730.231
DOI:
10.3969/j.issn.1672-4992.2025.03.019
Abstract:
As a member of the Ezrin-Radixin-Moesin (ERM) family,moesin is a link protein between cell membrane and cytoskeleton,which is involved in the maintenance of cell morphology and integrity and the formation of specialized cell surface structures.It also regulates cell adhesion,growth,and migration by regulating cell signal transduction.Moesin not only plays a key role in the regulation of vascular endothelial cells,but also participates in the occurrence and development of immune system diseases through cytoskeleton and cell signal transduction.At the same time,studies have found that moesin is closely related to the occurrence,development and prognosis of breast cancer,liver cancer,gastric cancer,colorectal cancer,glioma and other tumors.And moesin is expected to become a potential tumor molecular marker which is related to tumor prognosis.This article reviews the research progress of moesin in various tumors.

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Memo:
National Natural Science Foundation of China(No.82170183）；国家自然科学基金资助项目（编号：82170183）
Last Update: 1900-01-01