|Table of Contents|

Clinicopathological characteristics of primary pulmonary meningioma(1 case report)

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2025 03
Page:
423-426
Research Field:
Publishing date:

Info

Title:
Clinicopathological characteristics of primary pulmonary meningioma(1 case report)
Author(s):
LIU Ling1; WEI Li1; WANG Yijuan1; QIAO Senyan1; LIU Peng1; XIAO Bo1; LIU Mengmeng1; KONG Tiandong2
1.Department of Pathology;2.Department of Medical Oncology,the Third People's Hospital of Zhengzhou,Henan Zhengzhou 450003,China.
Keywords:
primary pulmonary meningiomas; pathological features; immunochemistry
PACS:
R734.2
DOI:
10.3969/j.issn.1672-4992.2025.03.010
Abstract:
Objective:To explore the clinical characteristics,pathological features,immunophenotype,diagnosis,and differential diagnosis of a case of primary meningioma of the lung,in order to improve understanding of primary pulmonary meningiomas(PPMs).Methods:We present a case of a male patient diagnosed with primary pulmonary meningioma,for which we conduct a retrospective analysis of the patient's clinical manifestation,histopathological features,and immunophenotype,as well as a thorough review of related literature.Results:PPM is very rare.Upon histological examination,the tumor consisted of spindle and epithelioid cells arranged in fascicles and swirls,partially surrounding blood vessels.The boundaries of the tumor cells were indistinct and contained pseudoinclusion bodies,scattered plasma cells,lymphocytes,and partially invaginated bronchioles.The tumor showed no evidence of hemorrhage,necrosis,or mitotic figures.Immunohistochemical analysis revealed that the tumor expressed S100 sporadically,SSTR2 and MUC-4 partially,while being focally positive for PR and CR.Ki-67 expression was less than 5%,and all other antibodies were negative.The results excluded the possibility of metastasis and led to a diagnosis of primary pulmonary meningioma.Conclusion：In summary,PPM is an uncommon form of ectopic meningioma,which can be differentiated from other tumors by its specific imaging and histological characteristics.Accurate diagnosis can be facilitated by a combination of complete tumor removal and immunohistochemical examination.

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