|Table of Contents|

Research progress and prospect of the effects of microgravity and radiation on cancer in space environment

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 21
Page:
4183-4188
Research Field:
Publishing date:

Info

Title:
Research progress and prospect of the effects of microgravity and radiation on cancer in space environment
Author(s):
YAN Yufan1CHEN Zhihao2LIU Shuai2XU Ying2FENG Dan2YANG Hong2
1.Xi'an Medical University,Shaanxi Xi'an 710021,China;2.The First Affiliated Hospital of Air Force Medical University,Shaanxi Xi'an 710032,China.
Keywords:
space environmentmicrogravityspace radiationcancergynecological tumor
PACS:
R730
DOI:
10.3969/j.issn.1672-4992.2024.21.031
Abstract:
The space environment has a special impact on astronaut health,providing a unique environment of stressors such as microgravity and space radiation.Although the carcinogenic risk of microgravity for astronauts is still unknown,it has unique effects on cancer cells,including the formation of multicellular spheres,cytoskeletal rearrangement,changes in adhesion,invasion and proliferation,and apoptosis.In addition,space radiation increases the risk of cancer.This review focuses on the effects of microgravity and radiation on common cancers,particularly gynecological cancers,to provide an overview of existing research on cancer risk,explore new paths for cancer treatment and prevention,and look forward to future cancer research in the space environment.

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Memo

Memo:
National Natural Science Foundation of China(No.82172993,32101055);国家自然科学基金(编号:82172993,32101055);空军军医大学第一附属医院医务人员培养助推项目(编号:XJZT24CY11)
Last Update: 2024-09-30