|Table of Contents|

Study on the external boundary of the planning target volume in different parts based on cone beam CT

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 18
Page:
3549-3555
Research Field:
Publishing date:

Info

Title:
Study on the external boundary of the planning target volume in different parts based on cone beam CT
Author(s):
ZHAO Liang1; 2; MA Chao1; MIN Xiao1; XIONG Bing1; WU Yan1; YANG Aimin2
1.Oncology Radiotherapy Department,Shaanxi Forest Industry Staff Hospital,Shaanxi Xi'an 710300,China;2.The First Affiliated Hospital of Xi'an Jiaotong University,Shaanxi Xi'an 710061,China.
Keywords:
kV-level cone beam CT; positioning error; image registration; external boundary
PACS:
R730.55
DOI:
10.3969/j.issn.1672-4992.2024.18.024
Abstract:
Objective:Based on kV-level cone beam CT (CBCT) image guidance technology,the positioning errors of radiotherapy were corrected,and the positioning errors in different directions were statistically analyzed,so as to determine the external boundary of the planning target volume in different parts of the human body.Methods:A total of 120 patients with head,neck and chest,chest and abdomen tumors were selected.During the treatment period of each patient,the 1st,6th,11th,16th,21st,...for each treatment,CBCT scanning and registration were performed every five times before treatment,the positioning errors were obtained,and PTV external boundary was calculated.Results:The positioning errors(mean±standard deviation) in the three directions of X-axis,Y-axis and Z-axis in different parts were X-axis (1.06±0.08),Y-axis (1.45±1.06),Z-axis (0.87±0.62) for head,X-axis (1.71±1.24),Y-axis (2.14±1.22),Z-axis (1.65±1.17) for neck and chest,X-axis (1.62±1.19),Y-axis (1.56±1.15),Z-axis (1.43±1.00) for chest,and X-axis (1.30±1.07),Y-axis (1.61±1.21),Z-axis (1.42±1.01) for abdomen.The margin from the clinical target volume (CTV) to the planning target volume (PTV) in the X,Y and Z axes was 2.53 mm,2.96 mm and 1.66 mm for head,2.84 mm,2.71 mm,2.67 mm for neck and chest,2.47 mm,2.38 mm,2.39 mm for chest,2.38 mm,2.40 mm,2.11 mm for abdomen.Conclusion:The external boundary of the PTV based on the positioning error of CBCT is of guiding significance in clinical radiotherapy.

References:

［1］ WANG W,XU R,LI J.CBCT guided interfraction absolute displacement and setup error assessment during breast prone radiotherapy［J］.International Journal of Radiation Oncology,Biology,Physics,2023,117(2S):e735.
［2］ 王云刚,闫先瑞,杨保成,等.胸部和腹部肿瘤患者不同放疗摆位技术精准度对比分析［J］.中华肿瘤防治杂志,2024,31(03):167-172. WANG YG,YAN XR,YANG BC,et al.Comparative analysis of the accuracy of different radiotherapy positioning techniques in patients with thoracic and abdominal tumors ［J］.Chinese Journal of Cancer Prevention,2024,31(03):167-172.
［3］ 俞雅,许青,韩序,等.锥形束CT图像引导在盆腔肿瘤患者调强放射治疗中位置误差测定的应用分析［J］.中国医学装备,2020,17(12):48-51. YU Y,XU Q,HAN X,et al.Application of conical beam CT image guidance in the determination of position error in intensity modulated radiation therapy for pelvic tumor patients ［J］.Chinese Medical Equipment,2020,17(12):48-51.
［4］ 罗翼,胡项英,廖志春,等.应用正态分布方法研究各部位肿瘤放射治疗摆位误差及PTV的外放边界［J］.医疗装备,2019,32(01):22-24. LUO Y,HU XY,LIAO ZC,et al.Application of normal distribution method to study the positioning error of radiotherapy and the external boundary of PTV［J］.Medical Equipment,2019,32(01):22-24.
［5］ 方亚玲,汪志,唐虹,等.腹部肿瘤调强放射治疗摆位中基于锥形束CT的误差［J］.医疗装备,2019,32(19):3-5. FANG YL,WANG Z,TANG H,et al.Error based on conical beam CT in placement of intensity modulated radiation therapy for abdominal tumors ［J］.Medical Equipment,2019,32(19):3-5.
［6］ AUWAL A,IMRAN SS,KHAIRIAH NKA,et al.Comparison of cone beam computed tomography (CBCT)-based image guided radiotherapy approaches in the reduction of setup uncertainties during deep inspiration breath-hold radiotherapy(DIBH-RT) for left breast cancer［J］.Radiation Physics and Chemistry,2023,212:1111.
［7］ 罗学臣,李雪南,沙翔燕,等.基于锥形束CT研究头颈部肿瘤调强放射治疗的计划靶区外放边界［J］.中国医学装备,2018,15(04):50-52. LUO XC,LI XN,SHA XY,et al.Study of planned target boundary of intensity-modulated radiation therapy for head and neck tumors based on conical beam CT［J］.Chinese Medical Equipment,2018,15(04):50-52.
［8］ 刘毅.千伏级锥形束CT引导对胸部肿瘤放疗中摆位误差及外放PTV边界的影响［J］.黑龙江医学,2018,42(07):708-709. LIU Y.Influence of KV-level conical beam CT guidance on positioning error and external PTV boundary in thoracic tumor radiotherapy ［J］.Heilongjiang Medical Journal,2018,42(07):708-709.
［9］ 周勇,江泽莹,苏宝锋,等.直线加速器机载千伏级扇形束CT和兆伏级锥形束CT系统在放疗摆位误差中的应用［J］.肿瘤防治研究,2023,50(11):1097-1102. ZHOU Y,JIANG ZY,SU BF,et al.Application of KV-class fan-beam CT and mega-volt cone-beam CT systems in linear accelerator for radiotherapy positioning errors ［J］.Cancer Prevention and Treatment Research,2023,50(11):1097-1102.
［10］LI Z,WU M,KONG F,et al.Investigation on cone-beam computed tomography-based liver cancer radiotherapy clinical target volume planning target volume margin and analysis of dosimetric differences［J］.Journal of Radiation Research and Applied Sciences,2023,16(2):100537.
［11］齐英男,麦秀滢,姜晓勃,等.食管癌个体化临床靶区-计划靶区外扩边界剂量研究及摆位误差分析［J］.中国医学物理学杂志,2023,40(12):1453-1458. QI YN,MAI XY,JIANG XB,et al.Study of individualized clinical target area and planned target area expanded boundary dose and analysis of positioning error for esophageal cancer ［J］.Chinese Journal of Medical Physics,2023,40(12):1453-1458.
［12］牛瑞军,张晖,陶娜,等.CBCT在线校准技术对宫颈癌术后调强放射治疗外放边界影响及剂量学差异分析［J］.辐射研究与辐射工艺学报,2018,36(06):11-19. NIU RJ,ZHANG H,TAO N,et al.Effect of CBCT online calibration technology on the external radiation boundary and dosimetry difference of postoperative intensive-modulated radiation therapy for cervical cancer ［J］.Journal of Radiation Research and Radiation Technology,2018,36(06):11-19.
［13］VAN HERK M,REMEIJER P,RASCH C,et al．The probability of correct target dosage：Dose-population histograms for deriving treatment margins in radiotherapy［J］.Int J Radiat Oncol Biol Phys,2000，47(4):1121-1135．
［14］MARCEL HV.Errors and margins in radiotherapy［J］.Seminars in Radiation Oncology,2004,14(1):52-54.
［15］ YANIK R,DIRICAN B.Evaluation of the effect of cone beam computed tomography (CBCT) system in adaptive radiotherapy (ART) lung plans［J］.Journal of Radiation Research and Applied Sciences,2024,17(2):100843.
［16］ ADAM DY,ANNIE C,MANUEL M,et al.Empirical analysis of a plan-of-the-day strategy to approximate daily online reoptimization for prostate CBCT-guided adaptive radiotherapy［J］.Journal of Applied Clinical Medical Physics,2023,25(1):e14221.
［17］ NIMA E,RUIQI L,ARUN D,et al.CBCT-guided adaptive radiotherapy using self-supervised sequential domain adaptation with uncertainty estimation［J］.Medical Image Analysis,2023,86:102800.
［18］ MBANGULA LA,ELIANA OV,FREDERICK AG,et al.Identification of patterns of tumour change measured on CBCT images in NSCLC patients during radiotherapy［J］.Physics in Medicine Andbiology,2020,65(21):215001.
［19］ 张克波,赵博.应用锥形束CT对减少宫颈癌及子宫内膜癌术后放疗摆位误差的效果研究［J］.大医生,2023,8(19):113-116. ZHANG KB,ZHAO B.Effect of cone beam CT on reducing positioning errors of postoperative radiotherapy for cervical and endometrial cancer ［J］.The Great Doctor,2023,8(19):113-116.
［20］ KIRAN C,DANIEL KE,KATHERINE T,et al.Assessment of bladder filling during prostate cancer radiation therapy with ultrasound and cone-beam CT［J］.Frontiers in Oncology,2023,13:1200270.
［21］ GIANLUCA F,VALENTINA Z,VITO V,et al.Towards personalization of planning target volume margins fitted to the abdominal adiposity in localized prostate cancer patients receiving definitive or adjuvant/salvage radiotherapy:Suggestive data from an ExacTrac vs.CBCT comparison［J］.Anticancer Research,2023,43(9):4077-4088.
［22］ PANG PPE,KNIGHT K,HUSSAIN A,et al.Reduction of intra-fraction prostate motion-Determining optimal bladder volume and filling for prostate radiotherapy using daily 4D TPUS and CBCT［J］.Technical Innovations & Patient Support in Radiation Oncology,2018,5:9-15.

Memo

Memo:
-
Last Update: 1900-01-01