|Table of Contents|

Comparative analysis of contrast-enhanced ultrasound and contrast-enhanced magnetic resonance imaging of mixed hepatocellular carcinoma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 15
Page:
2826-2832
Research Field:
Publishing date:

Info

Title:
Comparative analysis of contrast-enhanced ultrasound and contrast-enhanced magnetic resonance imaging of mixed hepatocellular carcinoma
Author(s):
CHEN Jianan1; ZHU Yuli2; CHEN Yanling3; BAO Jingwen4; XUE Zhixia1
1.The First Affiliated Hospital of Guangdong Pharmaceutical University,Guangdong Guangzhou 510000,China;2.Department of Ultrasound,Zhongshan Hospital,Fudan University,Shanghai 200032,China;3.The First Affiliated Hospital,Sun Yat-Sen University,Guangdong Guangzhou 510000,China;4.School of Medical Science,Hexi University,Gansu Zhangye 734000,China.
Keywords:
combined hepatocellular-cholangiocarcinoma; contrast-enhanced ultrasound; contrast-enhanced magnetic resonance imaging
PACS:
R735.7
DOI:
10.3969/j.issn.1672-4992.2024.15.021
Abstract:
Objective:To investigate the imaging characteristics of combined hepatocellular-cholangiocarcinoma(cHCC-ICC) in contrast-enhanced ultrasound(CEUS) and contrast-enhanced magnetic resonance imaging(CE-MRI),and evaluate the diagnostic value of the combination of serum tumor marker,CEUS,and CE-MRI manifestation for cHCC-ICC.Methods:Retrospectively analyzed the CEUS and CE-MRI imaging characteristics of 86 patients with pathologically confirmed cHCC-ICC.Took "simultaneous elevation of AFP and CA19-9","discordance of enhancement pattern in CEUS or CE-MRI with elevated serum tumor marker","discordance of enhancement patterns in CEUS and CE-MRI" and the combination of the above criteria as the diagnostic criteria for cHCC-ICC,and calculated corresponding diagnostic ccuracies.Results:On CEUS,there were 36.0% and 64.0% of cHCC-ICC lesions showed an HCC-like pattern and ICC-like pattern,while the ratio on CE-MRI was 40.7% and 59.3%,respectively.No significant difference was found between the two imaging modalities.There were 8.1% of cHCC-ICC patients showed simultaneous elevation of serum AFP and CA19-9,38.4% of patients had inconsistent CEUS finding and elevated tumor markers,41.9% of patients had inconsistent CE-MRI presentation and elevated tumor markers,51.2% of nodules had discordance in CEUS and CE-MRI manifestation,and 74.4% of cHCC-ICC could be detected with the combination of diagnostic criteria mentioned above.Conclusion:cHCC-ICC shared overlapped imaging features with HCC and ICC.On CEUS and CE-MRI,cHCC-ICC tended to present as ICC-like pattern.The combination of serum tumor markers,CEUS,and CE-MRI help to make diagnosis of cHCC-ICC.

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上海市卫生健康委员会科研项目（编号：202340087）
Last Update: 2024-06-28