|Table of Contents|

Progress in the role of Wnt / β -catenin signaling in non-small cell lung cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 03
Page:
577-583
Research Field:
Publishing date:

Info

Title:
Progress in the role of Wnt / β -catenin signaling in non-small cell lung cancer
Author(s):
SHEN Qi1ZHANG Lingfang1HU Han1WANG Yang1LIU Binlei12
1.Faculty of Bioengineering and Food,Hubei University of Technology,Hubei Wuhan 430068,China;2.Wuhan Binhui Biotechnology Company Limited,Hubei Wuhan 436030,China.
Keywords:
non-small cell lung cancerWnt/β-catenin signaling pathwaytargeted therapytumor immunity
PACS:
R734.2
DOI:
10.3969/j.issn.1672-4992.2024.03.035
Abstract:
Wnt/β-catenin signaling pathway plays an important role in embryonic development and cell proliferation,differentiation,and other physiological processes.It also plays a crucial role in the maintenance of cancer stem cells (CSCs),angiogenesis and epithelial-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC).Several studies have confirmed that Wnt/β-catenin signaling pathway is significantly activated in NSCLC.With the study of Wnt/β-catenin signaling pathway,targeted Wnt/β-catenin signaling pathway therapy has achieved remarkable results in the treatment of NSCLC.This article reviews the role and treatment of Wnt/β-catenin signaling pathway in the occurrence and development of NSCLC.

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Memo

Memo:
National Natural Science Foundation of China(No.82001758);国家自然科学基金青年基金项目(编号:82001758)
Last Update: 2023-12-29