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Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:

2024 03

Page:

558-560

Research Field:

Publishing date:

Info

Title:

Evaluation of FOxTROT phase III clinical trial of neoadjuvant chemotherapy for locally advanced colon cancer

Author(s):

XUE Dong; SUN Qi; WANG Guanghui

Department of General Surgery,the First Affiliated Hospital of Xi'an Jiaotong University,Shaanxi Xi'an 710061,China.

Keywords:

colon cancer; locally advanced; neoadjuvant chemotherapy; FOxTROT

PACS:

R735.3+5

DOI:

10.3969/j.issn.1672-4992.2024.03.031

Abstract:

At present,there is still a blank in neoadjuvant chemotherapy for locally advanced colon cancer.FOxTROT is the first phase III trial to evaluate the effectiveness of neoadjuvant chemotherapy strategy for locally advanced colon cancer,which fills the blank in this field.The results of FOxTROT show that neoadjuvant chemotherapy for 6 weeks before operation is reasonable,which significantly reduces the histopathological staging,improves the resection rate of R0,and reduces the 2-year recurrence rate of colon cancer after operation.Because of the limitations of FOxTROT research,it cannot represent the new standard of neoadjuvant chemotherapy for locally advanced colon cancer,but anoption.

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Memo

Memo:

National Natural Science Foundation of China£¨No.81803026£©;¹ú¼Ò×ÔÈ»¿Æѧ»ù½ðÏîÄ¿£¨±àºÅ£º81803026£©

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Last Update: 2023-12-29