|Table of Contents|

Research progress on the occurrence and development of clear cell renal cell carcinoma based on single-cell RNA sequencing technology

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 23
Page:
4436-4440
Research Field:
Publishing date:

Info

Title:
Research progress on the occurrence and development of clear cell renal cell carcinoma based on single-cell RNA sequencing technology
Author(s):
SHEN ChongZHAO Jianjun
College of Clinical Medicine,Hebei University of Engineering,Hebei Handan 056004,China.
Keywords:
clear cell renal cell carcinomasingle-cell RNA sequencingimmune infiltrationrecurrent and metastasis
PACS:
R737.11
DOI:
10.3969/j.issn.1672-4992.2023.23.027
Abstract:
Single-cell RNA sequencing(scRNA-seq) is an emerging technology that can precisely analyze the entire transcriptome of a single somatic cell.Based on single cell transcriptome sequencing,gene expression profiling of clear cell renal cell carcinoma(ccRCC) can reveal the origin,intratumoral heterogeneity and metastatic recurrence mechanism of ccRCC,which has important implications for the pathogenesis,individualized treatment and prognosis of ccRCC.This article provides a brief introduction to the latest research advances in single-cell transcriptome sequencing technology and focuses on its research progress in ccRCC.It is intended to help newcomers to enter the field rapidly as well as to gain a deeper understanding of the current state of research in this neighborhood to date.

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Memo

Memo:
河北省自然科学基金资助项目(编号:H2021402018)
Last Update: 2023-10-31