|Table of Contents|

Advances in the prediction of differentiated thyroid carcinoma metastasis by stimulating thyroglobulin before 131I treatment for the first time

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 21
Page:
4073-4077
Research Field:
Publishing date:

Info

Title:
Advances in the prediction of differentiated thyroid carcinoma metastasis by stimulating thyroglobulin before 131I treatment for the first time
Author(s):
LI MingFU Peng
Department of Nuclear Medicine,the First Affiliated Hospital of Harbin Medical University,Heilongjiang Harbin 150000,China.
Keywords:
differentiated thyroid carcinomastimulating thyroglobulinradioiodine therapy
PACS:
R736.1
DOI:
10.3969/j.issn.1672-4992.2023.21.032
Abstract:
Thyroglobulin(Tg) is a specific and sensitive indicator for monitoring recurrence or persistence in patients with differentiated thyroid cancer(DTC) during follow-up.Stimulating thyroglobulin(sTg) refers to serum Tg determined at elevated levels of thyroid stimulating hormone(TSH)>30 μIU/mL.sTg includes sTg after operation or before 131I treatment and sTg after thyroid remnant ablation.Previously,postablative sTg is well accepted as an important indicator for monitoring residual or recurrent disease.But preablative sTg(ps-Tg) is susceptible to factors such as TSH,residual thyroid and thyroglobulin antibody,so its value in assessing the condition of DTC and formulating a reasonable treatment plan is still controversial.However,recent studies have shown that ps-Tg can be used as an index to predict whether there is metastasis in DTC before the first 131I treatment,and provide a basis for the formulation of individualized 131I treatment in patients with DTC after operation.Therefore,this article mainly reviews the predictive value of ps-Tg in metastasis of DTC.

References:

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Last Update: 2023-09-28