|Table of Contents|

Research progress of non-coding RNA targeting glucose metabolism reprogramming in lung cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 14
Page:
2727-2732
Research Field:
Publishing date:

Info

Title:
Research progress of non-coding RNA targeting glucose metabolism reprogramming in lung cancer
Author(s):
WANG Yumin; ZOU Wailong; WU Xiaorui; LI Yulin; REN Zhao; CHEN Jichao
Department of Respiratory and Critical Care Medicine，Aerospace Center Hospital，Peking University Aerospace School of Clinical Medicine,Beijing 100049，China.
Keywords:
lung cancer; non-coding RNA; glucose metabolic reprogramming; Warburg effect; glycolysis
PACS:
R734.2
DOI:
10.3969/j.issn.1672-4992.2023.14.031
Abstract:
Lung cancer is one of the most common cancers and the leading cause of cancer-related death worldwide.Tumor cells often alter their metabolism in response to the changes in their environment,known as metabolic reprogramming,which is considered to be one of the top characteristics of tumor cells.Glucose metabolism is an important components of metabolic reprogramming.A large number of experimental studies have shown that non-coding RNA,such as microRNA(miRNA),long non-coding RNA(lncRNA),and circular RNA(circRNA) have been found to be dysregulated to affect lung cancer tumorigenesis and metastasis through glycolysis.The current review briefly introduces the regulatory effect of ncRNA on glucose metabolism of lung cancer cells,and the recent progress in elucidating the molecular mechanism of glucose metabolic remodeling in lung cancer,hoping to provide new strategies for clinical targeting tumor therapy.

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