|Table of Contents|

The progress of circular RNAs in neuroblastoma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 12
Page:
2353-2356
Research Field:
Publishing date:

Info

Title:
The progress of circular RNAs in neuroblastoma
Author(s):
ZHANG Xiaowen1; 2; CHEN Zimin2
1.Shantou University Medical College，Guangdong Shantou 515041，China；2.Department of General Surgery,Shenzhen Children's Hospital，Guangdong Shenzhen 518034，China.
Keywords:
circRNAs; microRNA; neuroblastoma; therapeutic target
PACS:
R739.4
DOI:
10.3969/j.issn.1672-4992.2023.12.032
Abstract:
Circular RNAs (circRNAs) comprise a group of noncoding RNAs formed by reverse splicing of mRNA precursors and are involved in different biological functions.They are extremely stable and expressed specifically in organs and tissues.circRNAs have primary functions such as microRNA sponges,RNA-binding protein and transcriptional regulatory protein,and translational templates.The abnormal expression of circRNAs has been reported in many human diseases including neuroblastoma (NB).Therefore,we briefly summarize their fundamental rules of regulating process as well as the mechanism.More importantly,we mainly review the current research progress of circRNAs in NB with a focus on the potential application for NB diagnosis,therapy and prognosis.

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Memo

Memo:
广东省医学科学技术研究基金项目（编号：A2020562）；深圳市医疗卫生三名工程（编号：SZSM201812055）；深圳市医学重点学科（2020-2024年）（编号：SZXK035）
Last Update: 1900-01-01