|Table of Contents|

Research progress of the relationship between the microbiome in tumor tissue and tumor

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 12
Page:
2335-2339
Research Field:
Publishing date:

Info

Title:
Research progress of the relationship between the microbiome in tumor tissue and tumor
Author(s):
CHEN Yuning1; YAN Yunyu2; WEI Wenbin1
1.Beijing Tongren Eye Center,Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment,Beijing Ophthalmology ＆ Visual Sciences Key Lab,Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China;2.CT Room,the Third Hospital of Hebei Medical University,Hebei Shijiazhuang 050051,China.
Keywords:
tumor; microbiome; oncogenesis; treatment; prognosis
PACS:
R730
DOI:
10.3969/j.issn.1672-4992.2023.12.029
Abstract:
The human microbiome is composed of microbes inside and on the surface of the body.The interaction between host and microorganisms affects many physiological processes and pathogenic factors.Most previous studies focused on the intestinal microbiome because of its richness and diversity.They found that it plays a vital role in the occurrence,development and treatment of malignant tumors,but little was known about the role of the microbiome in other parts of the body in tumors.Due to the development and application of 16S rRNA gene sequencing technology in the past decade,more and more scholars have found that intratumor bacteria are tumor type-specific in many types of tumors,and the local microbiome is also integral component of the tumor microenvironment.Furthermore,studies have shown that tumor-related microbiome may directly regulate the occurrence and progression of tumors and affect treatment efficacy.This article reviews the microbiome in tumor tissue and its effects on disease occurrence,development,diagnosis and treatment.

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Memo

Memo:
National Natural Science Foundation of China(No.82141128）；国家自然科学基金（编号：82141128）；首都卫生发展科研专项（编号：首发2020-1-2052）；北京市科委科技计划项目（编号：Z201100005520045，Z181100001818003）
Last Update: 1900-01-01