|Table of Contents|

Research progress on the mechanism of action and biological function of RNA binging proteins in the pathogenesis and development of renal cell carcinoma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 11
Page:
2155-2160
Research Field:
Publishing date:

Info

Title:
Research progress on the mechanism of action and biological function of RNA binging proteins in the pathogenesis and development of renal cell carcinoma
Author(s):
WANG BowenNI Shaobin
Department of Urology Surgery,the First Affiliated Hospital,Harbin Medical University,Heilongjiang Harbin 150001,China.
Keywords:
RNA binding proteinrenal cell carcinomamolecular markersreview
PACS:
R737.11
DOI:
10.3969/j.issn.1672-4992.2023.11.033
Abstract:
RNA binding proteins(RBPs) are an important component in gene regulation,which involve the interaction with rRNA,ncRNA,snRNA,miRNA,mRNA and tRNA.Dysregulation of its expression may promote cell proliferation,promote angiogenesis and inhibit apoptosis,which plays a key role in the occurrence and development of many diseases,especially malignant tumors.With the deepening of the research on the molecular mechanism of renal cell carcinoma,it has been found that the abnormal expression of RBPs is closely related to the proliferation,invasion and metastasis of renal cell carcinoma.These studies provide some new ideas for the diagnosis,treatment and prognosis evaluation of renal cell carcinoma.This article reviews the role of RNA-binding proteins in the development of renal cell carcinoma and their biological functions.

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Last Update: 2023-04-28