|Table of Contents|

Research progress of HPV infection in oral squamous cell carcinoma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 10
Page:
1952-1956
Research Field:
Publishing date:

Info

Title:
Research progress of HPV infection in oral squamous cell carcinoma
Author(s):
ZANG Xiyan1; WANG Junrong2; LIU Dongxu1; WU Kehan1; GAO Li1
1.Department of Oral and Maxillofacial Surgery，the Second Affiliated Hospital of Harbin Medical University，Heilongjiang Harbin 150081，China;2.Department of Head and Neck Tumors,Harbin Medical University Cancer Hospital,Heilongjiang Harbin 150081，China.
Keywords:
HPV; oral squamous cell carcinoma; head and neck cancer; pathogenesis
PACS:
R739.8
DOI:
10.3969/j.issn.1672-4992.2023.10.036
Abstract:
Oral squamous cell carcinoma (OSCC) is the most common malignant tumor in the head and neck.It has poor prognosis and the overall 5 years survival rate is lower.The world health organization(WHO) predicts that the incidence rate of OSCC will continue to rise in the next decade.In addition to tobacco,betel nut,alcohol and other factors,human papillomavirus (HPV) infection has also been identified as a risk factor.HPV infection is closely related to the occurrence and prognosis of OSCC.Current studies show that HPV infection has gradually become the main pathogenic factor of OSCC.OSCC caused by HPV infection may become a relatively unique type of OSCC in pathogenesis,tumor microenvironment,biological behavior and prognosis.Through extensive literature review,the author summarized the research progress on the mechanism of HPV in OSCC,the characteristics of HPV positive OSCC,and the correlation between HPV and the treatment and prevention of OSCC.

References:

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黑龙江省卫生计生委科研课题（编号：2018032）
Last Update: 1900-01-01