［1］刘宗超,李哲轩,张阳.2020年全球癌症统计报告［J］.中华预防医学杂志,2021,55(3):398.
LIU ZC,LI ZX,ZHANG Y.Global cancer statistics report 2020［J］.Chinese Journal of Preventive Medicine,2021,55(3):398.
［2］BONAVIDA B.Sensitizing activities of nitric oxide donors for cancer resistance to anticancer therapeutic drugs［J］.Biochem Pharmacol，2020，176：113913.
［3］VANNINI F，KASHFI K，NATH N.The dual role of iNOS in cancer［J］.Redox Biol，2015，6：334-343.
［4］VONG LB，NAGASAKI Y.Nitric oxide nano-delivery systems for cancer therapeutics：Advances and challenges［J］.Antioxidants（Basel)，2020，9(9):791.
［5］AN J，HU YG，LI C，et al.A pH/ultrasound dual-response biomimetic nanoplatform for nitric oxide gas-sonodynamic combined therapy and repeated ultrasound for relieving hypoxia［J］.Biomaterials，2020，230：119636.
［6］SOMASUNDARAM V，BASUDHAR D，BHARADWAJ G，et al.Molecular mechanisms of nitric oxide in cancer progression，signal transduction，and metabolism［J］.Antioxid Redox Signal，2019，30(8)：1124-1143.
［7］KHAN FH，DERVAN E，BHATTACHARYYA DD，et al.The role of nitric oxide in cancer：master regulator or not［J］.Int J Mol Sci，2020，21(24):9393.
［8］HOLOTIUK VV，KRYZHANIVSKA AY，CHURPIY IK，et al.Role of nitric oxide in pathogenesis of tumor growth and its possible application in cancer treatment［J］.Exp Oncol，2019，41(3)：210-215.
［9］ALIMORADI H，GREISH K，GAMBLE AB，et al.Controlled delivery of nitric oxide for cancer therapy［J］.Pharm Nanotechnol，2019，7(4)：279-303.
［10］THOMAS S，LOWE JE，KNOWLES RG，et al.Factors affecting the DNA damaging activity of superoxide and nitric oxide［J］.Mutat Res，1998，402(1-2)：77-84.
［11］NGUYEN T，BRUNSON D，CRESPI CL，et al.DNA damage and mutation in human cells exposed to nitric oxide in vitro［J］.Proc Natl Acad Sci USA，1992，89(7)：3030-3034.
［12］ZHOU S，LIU Y，JIN L，et al.Estrogen enhances the cytotoxicity of PARP inhibitors on breast cancer cells through stimulating nitric oxide production［J］.J Steroid Biochem Mol Biol，2021，209：105853.
［13］HUGHES MN.Relationships between nitric oxide，nitroxyl ion，nitrosonium cation and peroxynitrite［J］.Biochemica et Biophysica，1999，1411(2-3)：263-272.
［14］KAMM A，PRZYCHODZEN P，KUBAN-JANKOWSKA A，et al.Nitric oxide and its derivatives in the cancer battlefield［J］.Nitric Oxide，2019，93：102-114.
［15］SQUADRITO GL，POSTLETHWAIT EM.On the hydrophobicity of nitrogen dioxide：could there be a "lens" effect for NO(2) reaction kinetics［J］.Nitric Oxide，2009，21(2)：104-109.
［16］CHOUDHARI SK，CHAUDHARY M，BAGDE S，et al.Nitric oxide and cancer：a review［J］.World J Surg Oncol，2013，11：118.
［17］BURKE AJ，SULLIVAN FJ，GILES FJ，et al.The Yin and Yang of nitric oxide in cancer progression［J］.Carcinogenesis，2013，34(3)：503-512.
［18］SONG JM，UPADHYAYA P，KASSIE F.Nitric oxide-donating aspirin（NO-Aspirin) suppresses lung tumorigenesis in vitro and in vivo and these effects are associated with modulation of the EGFR signaling pathway［J］.Carcinogenesis，2018，39(7)：911-920.
［19］BERMUDEZ E，FERNG SF，CASTRO CE，et al.DNA strand breaks caused by exposure to ozone and nitrogen dioxide［J］.Environ Res，1999，81(1)：72-80.
［20］GREEN DR.Overview：apoptotic signaling pathways in the immune system［J］.Immunol Rev，2003，193：5-9.
［21］SUH J，PAYVANDI F，EDELSTEIN LC，et al.Mechanisms of constitutive NF-kappaB activation in human prostate cancer cells［J］.Prostate，2002，52(3)：183-200.
［22］JEANNIN JF，LEON L，CORTIER M，et al.Nitric oxide-induced resistance or sensitization to death in tumor cells［J］.Nitric Oxide，2008，19(2)：158-163.
［23］SAHEBNASAGH A，SAGHAFI F，NEGINTAJI S，et al.Nitric oxide and immune responses in cancer：searching for new therapeutic strategies［J］.Current Medicinal Chemistry，2022，29(9)：1561-1595.
［24］BAUER JA，LUPICA JA，DIDONATO JA，et al.Nitric oxide inhibits NF-kappaB-mediated survival signaling：possible role in overcoming TRAIL resistance［J］.Anticancer Res，2020，40(12)：6751-6763.
［25］TAYLOR EL，MEGSON IL，HASLETT C，et al.Nitric oxide：a key regulator of myeloid inflammatory cell apoptosis［J］.Cell Death Differ，2003，10(4)：418-430.
［26］PELLEGRINO NE，GUVEN A，GRAY K，et al.The next frontier：Translational development of ubiquitination，sumoylation，and neddylation in cancer［J］.Int J Mol Sci，2022，23(7):3480.
［27］REUTERSHAN MH，MACHACEK MR，ALTMAN MD，et al.Discovery of MK-4688：an efficient inhibitor of the HDM2-p53 protein-protein interaction［J］.J Med Chem，2021，64(21)：16213-16241.
［28］HESS DT，MATSUMOTO A，KIM SO，et al.Protein S-nitrosylation：purview and parameters［J］.Nat Rev Mol Cell Biol，2005，6(2)：150-166.
［29］YU L，HU P，CHEN Y.Gas-generating nanoplatforms：material chemistry，multifunctionality，and gas therapy［J］.Adv Mater，2018，30(49)：1801964.
［30］CHEN J，ZHU Y，WU C，et al.Nanoplatform-based cascade engineering for cancer therapy［J］.Chem Soc Rev，2020，49(24)：9057-9094.
［31］ISLAM W，KIMURA S，ISLAM R，et al.EPR-effect enhancers strongly potentiate tumor-targeted delivery of nanomedicines to advanced cancers：further extension to enhancement of the therapeutic effect［J］.Journal of Personalized Medicine，2021，11(6)：487.
［32］GOTTESMAN MM，LAVI O，HALL MD，et al.Toward a better understanding of the complexity of cancer drug resistance［J］.Annu Rev Pharmacol Toxicol，2016，56：85-102.
［33］GUO R，TIAN Y，WANG Y，et al.Near-infrared laser-triggered nitric oxide nanogenerators for the reversal of multidrug resistance in cancer［J］.Advanced Functional Materials，2017，27(13)：1606398.
［34］JIN G，GAO Z，LIU Y，et al.Polymeric nitric oxide delivery nanoplatforms for treating cancer，cardiovascular diseases，and infection［J］.Advanced Healthcare Materials，2021，10(3)：2001550.
［35］DENG Y，JIA F，CHEN X，et al.ATP suppression by pH-activated mitochondria-targeted delivery of nitric oxide nanoplatform for drug resistance reversal and metastasis inhibition［J］.Small，2020，16(23)：2001747.
［36］WANG J，WU C，QIN X，et al.NIR-Ⅱ light triggered nitric oxide release nanoplatform combined chemo-photothermal therapy for overcoming multidrug resistant cancer［J］.J Mater Chem B，2021，9(6)：1698-1706.
［37］EISENHUT M.Evidence supporting the hypothesis that inflammation-induced vasospasm is involved in the pathogenesis of acquired sensorineural hearing loss［J］.Int J Otolaryngol，2019,2019：4367240.
［38］JAMESDANIEL S，RATHINAM R，NEUMANN WL.Targeting nitrative stress for attenuating cisplatin-induced downregulation of cochlear LIM domain only 4 and ototoxicity［J］.Redox Biol，2016，10：257-265.
［39］CHEN L，HE Q，LEI M，et al.Facile coordination-precipitation route to insoluble metal roussin's black salts for NIR-responsive release of NO for anti-metastasis［J］.ACS Applied Materials & Interfaces，2017，9(42)：36473-36477.
［40］WU W，YANG Y，LIANG Z，et al.Near infrared Ⅱ laser controlled free radical releasing nanogenerator for synergistic nitric oxide and alkyl radical therapy of breast cancer［J］.Nanoscale，2021，13(25)：11169-11187.
［41］LIU Y，BHATTARAI P，DAI Z，et al.Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer［J］.Chem Soc Rev，2019，48(7)：2053-2108.
［42］HUANG X，LU Y，GUO M，et al.Recent strategies for nano-based PTT combined with immunotherapy：from a biomaterial point of view［J］.Theranostics，2021，11(15)：7546-7569.
［43］QIAN X，ZHENG Y，CHEN Y.Micro/nanoparticle-augmented sonodynamic therapy（SDT)：breaking the depth shallow of photoactivation［J］.Advanced materials，2016，28(37)：8097-8129.
［44］PAN X，WANG H，WANG S，et al.Sonodynamic therapy（SDT)：a novel strategy for cancer nanotheranostics［J］.Sci China Life Sci，2018，61(4)：415-426.
［45］PAN X，WANG W，HUANG Z，et al.MOF-derived double-layer hollow nanoparticles with oxygen generation ability for multimodal imaging-guided sonodynamic therapy［J］.Angew Chem Int Ed Engl，2020，59(32)：13557-13561.
［46］ZHANG K，XU H，JIA X，et al.Ultrasound-triggered nitric oxide release platform based on energy transformation for targeted inhibition of pancreatic tumor［J］.ACS Nano，2016，10(12)：10816-10828.
［47］JI C，SI J，XU Y，et al.Mitochondria-targeted and ultrasound-responsive nanoparticles for oxygen and nitric oxide codelivery to reverse immunosuppression and enhance sonodynamic therapy for immune activation［J］.Theranostics，2021，11(17)：8587-8604.
［48］YAN P，LIU LH，WANG P.Sonodynamic therapy（SDT) for cancer treatment：advanced sensitizers by ultrasound activation to injury tumor［J］.ACS Appl Bio Mater，2020，3(6)：3456-3475.