|Table of Contents|

Research progress of sialylation and fucosylation in ovarian cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 03
Page:
561-566
Research Field:
Publishing date:

Info

Title:
Research progress of sialylation and fucosylation in ovarian cancer
Author(s):
PU CongliZHAO Yingchao
Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Hubei Wuhan 430000,China.
Keywords:
sialylationfucosylationovarian cancer
PACS:
R737.31
DOI:
10.3969/j.issn.1672-4992.2023.03.034
Abstract:
Glycosylation is one of the most important ways of post-translational modification,and participates in various activities such as cell adhesion,signal transduction,and immune regulation under physiological conditions.Ovarian cancer is the third largest malignant tumor threatening female reproductive health after breast cancer and cervical cancer.It's occurrence and development are accompanied by abnormal glycosylation modifications.Abnormal glycosylation is closely related to tumor growth,evasion of apoptosis,invasion and migration,and resistance to therapy.The up-regulation of sialylation and fucosylation are the most common types of abnormal glycosylation.The research progress of abnormal sialylation and fucosylation in ovarian cancer has important clinical significance for promoting early diagnosis,prognosis prediction and targeted therapy of ovarian cancer.

References:

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Memo

Memo:
National Natural Science Foundation of China(No.81974463);国家自然科学基金(编号:81974463)
Last Update: 1900-01-01