|Table of Contents|

Observation on clinical efficacy and safety of foot massage combined with electric moxibustion in the treatment of cancer-related fatigue (CRF) based on invigorating Qi and warming Yang theory:A parallel controlled study

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 02
Page:
347-353
Research Field:
Publishing date:

Info

Title:
Observation on clinical efficacy and safety of foot massage combined with electric moxibustion in the treatment of cancer-related fatigue (CRF) based on invigorating Qi and warming Yang theory:A parallel controlled study
Author(s):
LIU Peng1; 2; PENG Zhaowen2; YOU Hailin2; ZHONG Yuantao2; YI Shujing2; JIANG Yang2; HUANG Jinlan2; ZHUANG Biyun2; YE Shulin2; FENG Gaofei2; CAO Yang1; 3
1.The First Medical College of Guangzhou University of Chinese Medicine,Guangdong Guangzhou 510405,China;2.Oncology Department Shenzhen Hospital(Longgang),Beijing University of Chinese Medicine,Guangdong Shenzhen 518172,China;3.Cancer Center The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangdong Guangzhou 510405,China.
Keywords:
cancer-related fatigue(CRF); external treatment of Chinese Medicine; foot massage with Chinese Medicine; electric moxibustion; invigorating Qi and warming Yang; control study
PACS:
R273
DOI:
10.3969/j.issn.1672-4992.2023.02.029
Abstract:
Objective:To evaluate the clinical efficacy and safety of foot massage with Chinese medicine(CM)combined with electric moxibustion in the treatment of cancer-related fatigue(CRF)based on invigorating Qi and warming Yang theory.Methods:A total of 118 patients with CRF were collected in inpatient department of our hospital from August 2019 to March 2021.By taking a random number table method,the patients were divided into observation group A,observation group B and control group.The control group (40 cases) was treated with only symptomatic support.Group A (39 cases) adopted CM decoction foot massage combined with symptomatic support treatment,and group B(39 cases)received electric moxibustion additionally.The clinical efficacy,Piper fatigue Scale score,functional status score(KPS),quality of life(QOL,appetite,spirit,sleep,fatigue,pain,etc.)and T lymphocyte subsets of the three groups were compared,and the safety was evaluated from clinical symptoms,signs and routine examination.Results:The total effective rate of group A(82.1%,32/39)and B(89.7%,35/39)was higher than that of control group(57.5%,23/40)(P＜ 0.05).Group B was better than group A(P＜0.05).The improvement rate of KPS score was compared after treatment.Group A(79.5%,31/39)and group B(94.9%,37/39)were higher than those in control group(52.5%,31/39),and group B was superior to group A(P＜0.05).There was difference in Comparison of QOL score among the 3 groups before treatment(P＞0.05),intra-group comparison of 3 groups after treatment(P＜0.05).Group A and B were improved and better than control group(P＜0.05),and group B was superior to group A(P＜0.05).In the details of QOL scale,observation group A and B were superior to control group in 7 aspects of appetite,spirit,sleep,fatigue,attitude to treatment,daily life and facial expression after treatment(P＜0.05),and group B was superior to group A in spirit,sleep,fatigue and treatment side effects(P＜ 0.05).There was no different in comparison of the immune function of the three groups before treatment(P＞0.05).After treatment,the immune indexes of CD3+T,CD3+CD4+T,CD3+CD4+T/CD3+CD8+T and NK cells in groups A and B were better than those in control group(P＜0.05).NK cell status in group B was better than that in group A(P＜0.05).There was 1 case of grade I skin pruritus in group A,1 case of grade 1 blood pressure elevation in group B,and 1 case of treatment-related nausea and vomiting in control group.The adverse reaction rates of the three groups were not significant(P＞0.05).Conclusion:Combined application of foot massage with CM and electric moxibustion under the guidance of the theory of invigorating Qi and warming Yang can effectively improve the KPS,QOL and immune function of CRF patients,with good safety and worthy of further exploration and research.

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