|Table of Contents|

Application of liquid biopsy in endometrial cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2022 05
Page:
912-916
Research Field:
Publishing date:

Info

Title:
Application of liquid biopsy in endometrial cancer
Author(s):
JIA PengZHANG Yan
Peking University First Hospital,Beijing 100000,China.
Keywords:
endometrial cancerliquid biopsycirculating tumor cellscirculating tumor DNA
PACS:
R737.33
DOI:
10.3969/j.issn.1672-4992.2022.05.033
Abstract:
Endometrial cancer is one of the most common malignant tumors of the female reproductive system.Most endometrial cancers can be diagnosed at an early stage and have a good prognosis,but advanced and recurrent endometrial cancer has a poor prognosis.Liquid biopsy,as a minimally invasive way to obtain tumor specimens,has advantages such as noninvasive and reproducible acquisition,and is currently approved to be applied in the diagnosis and treatment process of multiple malignant tumors.At present,liquid biopsy also has relevant research and applications in the early diagnosis,risk stratification,treatment selection and real-time disease monitoring of endometrial cancer,and it holds great promise.

References:

[1] HENLEY SJ,WARD EM,SCOTT S,et al.Annual report to the nation on the status of cancer,part I:National cancer statistics[J].Cancer,2020,126(10):2225-2249.
[2] SIEGEL RL,MILLER KD,FUCHS HE,et al.Cancer statistics,2021[J].CA:a cancer journal for clinicians,2021,71(1):7-33.
[3] SUNG H,FERLAY J,SIEGEL RL,et al.Global cancer statistics 2020:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J].CA:a cancer journal for clinicians,2021,71(3):209-249.
[4] 郑荣寿,孙可欣,张思维,等.2015年中国恶性肿瘤流行情况分析[J].中华肿瘤杂志,2019,41(1):19-28. ZHENG RS,SUN KX,ZHANG SW,et al.Report of cancer epidemiology in China,2015[J].Chinese Journal of Oncology,2019,41(1):19-28.
[5] CANCER GENOME ATLAS RESEARCH NETWORK,KANDOTH C,SCHULTZ N,et al.Integrated genomic characterization of endometrial carcinoma [J].Nature,2013,497(7447):67-73.
[6] TALHOUK A,MCCONECHY MK,LEUNG S,et al.A clinically applicable molecular-based classification for endometrial cancers[J].British Journal of Cancer,2015,113(2):299-310.
[7] SMITH P,BAKOS O,HEIMER G,et al.Transvaginal ultrasound for identifying endometrial abnormality[J].Acta Obstetricia Et Gynecologica Scandinavica,1991,70(7-8):591-594.
[8] SAMS SB,CURRENS HS,RAAB SS.Liquid-based papanicolaou tests in endometrial carcinoma diagnosis.Performance,error root cause analysis,and quality improvement[J].American Journal of Clinical Pathology,2012,137(2):248-254.
[9] JIANG X,LI W,YANG J,et al.Identification of somatic mutations in papanicolaou smear DNA and plasma circulating cell-free DNA for detection of endometrial and epithelial ovarian cancers:a pilot study[J].Frontiers in Oncology,2020,10:582546.
[10] WANG Y,LI L,DOUVILLE C,et al.Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers[J].Science Translational Medicine,2018,10(433):eaap8793.
[11] CASAS-AROZAMENA C,DIAZ E,MOIOLA CP,et al.Genomic profiling of uterine aspirates and cfDNA as an integrative liquid biopsy strategy in endometrial cancer[J].Journal of Clinical Medicine,2020,9(2):585.
[12] NAIR N,CAMACHO-VANEGAS O,RYKUNOV D,et al.Genomic analysis of uterine lavage fluid detects early endometrial cancers and reveals a prevalent landscape of driver mutations in women without histopathologic evidence of cancer:a prospective cross-sectional study[J].PLoS Medicine,2016,13(12):e1002206.
[13] MARTIGNETTI JA,PANDYA D,NAGARSHETH N,et al.Detection of endometrial precancer by a targeted gynecologic cancer liquid biopsy[J].Cold Spring Harbor Molecular Case Studies,2018,4(6):a003269.
[14] ASHWORTH T.A case of cancer in which cells similar to those in the tumours were seen in the blood after death[J].Australasian Medical Journal,1869,14:146-147.
[15] PANTEL K,BRAKENHOFF RH.Dissecting the metastatic cascade[J].Nature Reviews Cancer,2004,4(6):448-456.
[16] GHOSSEIN RA,BHATTACHARYA S,ROSAI J.Molecular detection of micrometastases and circulating tumor cells in solid tumors[J].Clinical Cancer Research,1999,5(8):1950-1960.
[17] MANDEL P,METAIS P.Les acides nucléiques du plasma sanguin chez l’ homme [Nuclear Acids In Human Blood Plasma] [J].Comptes Rendus Des Seances De La Societe De Biologie Et De Ses Filiales,1948,142(3-4):241-243.
[18] FENG W,JIA N,JIAO H,et al.Circulating tumor DNA as a prognostic marker in high-risk endometrial cancer[J].Journal of Translational Medicine,2021,19(1):51.
[19] MAIDA Y,TAKAKURA M,NISHIUCHI T,et al.Exosomal transfer of functional small RNAs mediates cancer-stroma communication in human endometrium[J].Cancer Medicine,2016,5(2):304-314.
[20] DE BRUYN C,BAERT T,VAN DEN BOSCH T,et al.Circulating transcripts and biomarkers in uterine tumors:is there a predictive role [J].Current Oncology Reports,2020,22(2):12.
[21] TORRES A,TORRES K,PESCI A,et al.Deregulation of miR-100,miR-99a and miR-199b in tissues and plasma coexists with increased expression of mTOR kinase in endometrioid endometrial carcinoma[J].BMC Cancer,2012,12:369.
[22] TORRES A,TORRES K,PESCI A,et al.Diagnostic and prognostic significance of miRNA signatures in tissues and plasma of endometrioid endometrial carcinoma patients[J].International Journal of Cancer,2013,132(7):1633-1645.
[23] SRIVASTAVA A,MOXLEY K,RUSKIN R,et al.A Non-invasive liquid biopsy screening of urine-derived exosomes for mirnas as biomarkers in endometrial cancer patients[J].The AAPS journal,2018,20(5):82.
[24] KOMMOSS S,HARTKOPF AD,KRAMER B,et al.Disseminated tumor cells are not associated with established risk factors,L1CAM immunoreactivity and outcome in endometrial carcinoma[J].Journal of Cancer Research and Clinical Oncology,2017,143(11):2183-2188.
[25] WALTER CB,TARAN FA,WALLWIENER M,et al.Prevalence and prognostic value of disseminated tumor cells in primary endometrial,cervical and vulvar cancer patients[J].Future Oncology(London,England),2014,10(1):41-48.
[26] BOGANI G,LIU MC,DOWDY SC,et al.Detection of circulating tumor cells in high-risk endometrial cancer[J].Anticancer research,2015,35(2):683-687.
[27] NI T,SUN X,SHAN B,et al.Detection of circulating tumour cells may add value in endometrial cancer management[J].European Journal of Obstetrics Gynecology and Reproductive Biology,2016,207:1-4.
[28] ALONSO-ALCONADA L,MUINELO-ROMAY L,MADISSOO K,et al.Molecular profiling of circulating tumor cells links plasticity to the metastatic process in endometrial cancer[J].Molecular Cancer,2014,13:223.
[29] LEMECH CR,ENSELL L,PATERSON JC,et al.Enumeration and molecular characterisation of circulating tumour cells in endometrial cancer[J].Oncology,2016,91(1):48-54.
[30] LIN H,BALIC M,ZHENG S,et al.Disseminated and circulating tumor cells:Role in effective cancer management[J].Critical Reviews in Oncology/Hematology,2011,77(1):1-11.
[31] CICCHILLITTI L,CORRADO G,DE ANGELI M,et al.Circulating cell-free DNA content as blood based biomarker in endometrial cancer[J].Oncotarget,2017,8(70):115230-115243.
[32] DOBRZYCKA B,TERLIKOWSKI SJ,MAZUREK A,et al.Circulating free DNA,p53 antibody and mutations of KRAS gene in endometrial cancer[J].International Journal of Cancer,2010,127(3):612-621.
[33] MALENTACCHI F,TURRINI I,ZEPPONI F,et al.Mutational profile in circulating tumor DNA in a patient affected by low-risk endometrial cancer:predictable tool of relapse[J].Anticancer Drugs,2020,31(10):1091-1095.
[34] BOLIVAR AM,LUTHRA R,MEHROTRA M,et al.Targeted next-generation sequencing of endometrial cancer and matched circulating tumor DNA:identification of plasma-based,tumor-associated mutations in early stage patients[J].Modern Pathology,2019,32(3):405-414.
[35] SHINTANI D,HIHARA T,OGASAWARA A,et al.Tumor-related mutations in cell-free DNA in pre-operative plasma as a prognostic indicator of recurrence in endometrial cancer[J].International Journal of Gynecological Cancer,2020,30(9):1340-1346.
[36] VAN DEN HEERIK ASVM,HOREWEG N,DE BOER SM,et al.Adjuvant therapy for endometrial cancer in the era of molecular classification:radiotherapy,chemoradiation and novel targets for therapy[J].International Journal of Gynecological Cancer,2021,31(4):594-604.
[37] OTT PA,BANG YJ,BERTON-RIGAUD D,et al.Safety and antitumor activity of pembrolizumab in advanced programmed death ligand 1-positive endometrial cancer:results from the KEYNOTE-028 study[J].Journal of Clinical Oncology,2017,35(22):2535-2541.
[38] YU F,MAKRIGIORGOS A,LEONG KW,et al.Sensitive detection of microsatellite instability in tissues and liquid biopsies:Recent developments and updates[J].Computational and Structural Biotechnology Journal,2021,19:4931-4940.
[39] GILSON P,MERLIN JL,HARLE A.Detection of microsatellite instability:state of the art and future applications in circulating tumour DNA (ctDNA) [J].Cancers (Basel),2021,13(7):1491.
[40] MUSACCHIO L,CARUSO G,PISANO C,et al.PARP inhibitors in endometrial cancer:current status and perspectives[J].Cancer Management and Research,2020,12:6123-6135.
[41] ABBINK K,ZUSTERZEEL PL,GEURTS-MOESPOT AJ,et al.HE4 is superior to CA125 in the detection of recurrent disease in high-risk endometrial cancer patients[J].Tumour Bbiology,2018,40(2):1010428318757103.
[42] DIEHL F,SCHMIDT K,CHOTI MA,et al.Circulating mutant DNA to assess tumor dynamics[J].Nature Medicine,2008,14:985-990.
[43] MOSS EL,GORSIA DN,COLLINS A,et al.Utility of circulating tumor dna for detection and monitoring of endometrial cancer recurrence and progression[J].Cancers (Basel),2020,12(8):2231.

Memo

Memo:
-
Last Update: 2022-01-27