|Table of Contents|

Clinical observation of tonifying spleen and nourishing qi combined with erythropoietin treatment for advanced gastric cancer associated anemia

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2022 05
Page:
834-837
Research Field:
Publishing date:

Info

Title:
Clinical observation of tonifying spleen and nourishing qi combined with erythropoietin treatment for advanced gastric cancer associated anemia
Author(s):
ZHANG Wei; SUN Wei; ZOU Xi; HU Yue
Oncology Department,Jiangsu Province Hospital of Traditional Medicine,Nanjing University of Chinese Medicine,Jiangsu Nanjing 210093,China.
Keywords:
advanced gastric cancer; tonifying spleen and nourishing qi; tumor associated anemia; erythropoietin
PACS:
R735.2
DOI:
10.3969/j.issn.1672-4992.2022.05.016
Abstract:
Objective:To compare the efficacy between tonifying spleen and nourishing qi combined with erythropoietin with erythropoietin for patients with advanced gastric cancer associated anemia.Methods:A total of 44 patients with advanced gastric cancer were divided randomly into two groups.There were 22 patients for erythropoietin group(control group:treated with erythropoietin 150 IU/kg three times a week) and 22 patients for tonifying spleen and nourishing qi combinated erythropoietin group(treatment group:treated with erythropoietin 150 IU/kg three times a week and tonifying spleen and nourishing qi decoction).Both two groups were evaluated after 8 weeks.Results：There was significant difference before and after treatment on RBC,HGB and HCT in the treatment group(P＜0.05).Peripheral blood CD4+/CD8+ subset in treatment group was significantly higher(P＜0.05)．The KPS score,fatigue score and sicchasia,melancholian dysphoric,drowsy,orexia were improved significantly in treatment group(P＜0.05).Conclusion：Tonifying spleen and nourishing qi combined with erythropoietin is effective for gastric cancer associated anemia.

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Memo

Memo:
National Natural Science Foundation of China(No.81973782）；国家自然科学基金（编号:81973782）；江苏省重点研发计划专项资金项目（编号：BE2019771）
Last Update: 2022-01-27