|Table of Contents|

The effect of preoperative nutritional risk on the prognosis of patients with bladder cancer after radical cystectomy

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2022 02
Page:
281-285
Research Field:
Publishing date:

Info

Title:
The effect of preoperative nutritional risk on the prognosis of patients with bladder cancer after radical cystectomy
Author(s):
FU Weiqin; FU Guanghua; QIAN Wenyan
Department of Urology Surgery,the First People's Hospital of Yibin,Sichuan Yibin 664000,China.
Keywords:
nutritional risk; bladder cancer; radical cystectomy; prognosis
PACS:
R737.14
DOI:
10.3969/j.issn.1672-4992.2022.02.021
Abstract:
Objective：To explore the effect of preoperative nutritional risk on the prognosis of patients with bladder cancer after radical cystectomy.Methods:The clinical data of 186 patients with radical cystectomy admitted to department of urology surgery in our hospital from February 2010 to May 2018 were analyzed retrospectively.Nutritional Risk Screening-2002 (NRS-2002) was used to screen the patients with bladder cancer for nutritional risk.According to the NRS-2002 score,the patients were divided into the group with nutritional risk (total score≥3 points,n=96) and the group without nutritional risk (total score<3 points,n=90).The clinical data between the two groups were compared.Kaplan-Meier method was used to analyze the recurrence free survival (RFS) and overall survival (OS) between the two groups.The independent risk factors of RFS and OS were analyzed by the multivariate Cox proportional risk regression model.Results:There were significant differences in pathological T stage,tumor size,lymph node metastasis and hydronephrosis between the group with nutritional risk and the group without nutritional risk (P＜0.05).The 5-year RFS rates of the group with and without nutritional risk were 29.17%(28/96) and 45.56%(41/90),respectively.The 5-year OS rates of the group with and without nutritional risk were 43.75%(42/96) and 58.89%(53/90),respectively.Kaplan-Meier analysis showed that RFS and OS of patients with nutritional risk were shorter than those without nutritional risk (P＜0.05).The Cox proportional risk regression model showed that preoperative nutritional risk was an independent risk factor for RFS and OS in bladder cancer patients undergoing radical cystectomy (P＜0.05).Conclusion:Preoperative nutritional risk is an independent risk factor for RFS and OS in bladder cancer patients undergoing radical cystectomy.Patients with nutritional risk had worse prognosis.

References:

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