|Table of Contents|

Clinicopathological features and prognosis of young gastric cancer patients

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2021 06
Page:
998-1001
Research Field:
Publishing date:

Info

Title:
Clinicopathological features and prognosis of young gastric cancer patients
Author(s):
XIAO Yanping1; XIAO Hua2
1.Changsha Health Vocational College,Hunan Changsha 410010,China;2.Department of Gastrointestinal Surgery,Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine,Central South University,Hunan Changsha 410013,China.
Keywords:
gastric cancer; gastrectomy; age; prognosis
PACS:
R735.2
DOI:
10.3969/j.issn.1672-4992.2021.06.019
Abstract:
Objective:To investigate the clinicopathological features and prognosis of gastric cancer (GC) in young patients (≤35 years old).Methods:The clinicopathological data of 75 young patients (≤35 years old) and 1 954 older patients (>35 years old,control group) undergoing radical gastrectomy for stage Ⅰ-Ⅲ GC in Hunan Cancer Hospital from October 2010 to December 2017 were retrospectively reviewed.The difference of demographic characteristics,pathological results and long term survival between the two groups were compared by χ2 or t test (for categorical or continuous variables),or Kaplan-Meier method,Log-rank test and Cox proportional hazard regression analysis (for prognosis).Results:The mean age of the 75 young patients was 30.13 (19~35) years old,with a slight female predominance (53.3%).Compared with the older patients,young GC patients had a higher rate of female,higher pre-operative albumin level,lower proportions of comorbidities and post-operative complications,shorter post-operative hospital stays,but more likelihood of receiving neo-adjuvant and adjuvant chemotherapy (all P＜0.05).The 1-,3- and 5-year survival rates of the young patients were 94.6%,60.1% and 54.2%,which were comparable with those in the control group (89.3%,67.7% and 58.1%,P=0.601).Further analysis showed that pathological tumor stage was the main risk factor for prognosis of the young GC patients.Conclusion:GC in young patients trends to be female predominant.Given early detection,receiving radical gastrectomy and adjuvant chemotherapy,the prognosis of young GC patients is comparable with that in older patients.

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Memo

Memo:
湖南省自然科学基金青年基金项目（编号：2020JJ5339）；湖南省卫生健康委2020年度科研课题（编号：20200608）；长沙市科技计划项目（编号：kq1907125）
Last Update: 1900-01-01