|Table of Contents|

Comparison of effect between ultrasound-guided transversus thoracic muscle plane-pectoral nerves block and thoracic paravertebral nerve block in patients underdoing modified radical mastectomy

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2021 05
Page:
877-882
Research Field:
Publishing date:

Info

Title:
Comparison of effect between ultrasound-guided transversus thoracic muscle plane-pectoral nerves block and thoracic paravertebral nerve block in patients underdoing modified radical mastectomy
Author(s):
ZHAO Ying; FEI Jianping; LEI Yue; SHAO Anmin
Department of Anesthesiology,the Traditional Chinese Medicine Hospital of Kunshan,Jiangsu Kunshan 215300,China.
Keywords:
regional nerve block; tumor of breast; analgesia; inflammatory reaction; early outcomes
PACS:
R737.9
DOI:
10.3969/j.issn.1672-4992.2021.05.035
Abstract:
Objective:To compare the effect between ultrasound-guided transversus thoracic muscle plane-pectoral nerves block (TTP-PECS) and thoracic paravertebral nerve block (TPVB) in patients underdoing modified radical mastectomy.Methods:80 patients of female,age 28~74 years old,height 151~172 cm,weighing 47~72 kg,ASA Ⅰ-Ⅱ,scheduled for elective modified radical mastectomy,were randomly divided into two groups (n=40):TTP-PECS group (group TP) and TPVB group (group T).Ultrasound-guided TTP-PECS was performed in group TP and TPVB in group T.Intraoperative,PACU and postoperative 24 h PCIA fentanyl consumption,effective PCIA pressing,rate of postoperative remedial analgesia,as well as analgesia duration were compared.The levels of IL-6,MCP-1 and TNF-α,as well as PGE2,NPY and beta-endorphins were checked at different times.The relative indexes of postoperative outcomes were also compared.Results:Compared with group T,the postoperative 24 h PCIA fentanyl consumption,effective PCIA pressing,and rate of postoperative remedial analgesia were decreased,and the analgesia duration was increased.The levels of IL-6,MCP-1 and TNF-α,as well as PGE2,NPY and beta-endorphins were reduced at postoperation 12 h.The incidence of hypotension and bradycardia,the scores of 12 h daily sleep interference scale,and the time of first ambulation were significantly reduced in group TP (P＜0.05).Conclusion:Compared with TPVB,ultrasound-guided TTP-PECS can provide better postoperative analgesia,better inhibit postoperative inflammatory reaction and promote early outcomes in patients underdoing modified radical mastectomy.

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Last Update: 2021-01-29