|Table of Contents|

The comparison of the quality of life underwent three different surgical procedures for advanced Siewert type Ⅱ adenocarcinomas of the esophagogastric junction

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2021 05
Page:
782-786
Research Field:
Publishing date:

Info

Title:
The comparison of the quality of life underwent three different surgical procedures for advanced Siewert type Ⅱ adenocarcinomas of the esophagogastric junction
Author(s):
DU Ning1; WANG Rui1; PENG Ziyang1; HU Xiayun1; LIAO Xinhua2; SUN Xin1; REN Hong1; LIU Dapeng1
1.Department of Thoracic Surgery；2.Department of General Surgery,the First Affiliated Hospital of Xi'an Jiaotong University,Shaanxi Xi'an 710061,China.
Keywords:
adenocarcinoma of esophagogastric junction; mode of operation; quality of life
PACS:
R735.1；R735.2
DOI:
10.3969/j.issn.1672-4992.2021.05.014
Abstract:
Objective:To compare the quality of life of three different surgical procedures for advanced Siewert type Ⅱ adenocarcinomas of the esophagogastric junction,so as to provide theoretical basis for optimizing the surgical treatment of patients with advanced Siewert type Ⅱadenocarcinomas of the esophagogastric junction.Methods:105 patients with advanced Siewert Ⅱadenocarcinomas of the esophagogastric junction treated in the First Affiliated Hospital of Xi'an Jiaotong University from October 2015 to October 2017 were selected.According to the operation,the patients were divided into three groups:Total gastrectomy group（A group),traditional proximal gastrectomy group（B group) and double channel anastomosis group（C group).After quantification with the total quality of life scale（quality of life questionnaire core-30,QLQ-C30) and the esophagogastric junction cancer scale（quality of life questionnaire oesophagogastric-25,QLQ-OG25),the quality of life of the three groups were compared half a year and one year after operation.Results:QLQ-C30 showed in six months after operation,the scores of overall quality of life,physical function,fatigue and dyspnea in group C were better than those in group A and group B,while the scores of emotional function in group C were better than those in group A（P＜0.05).The scores of role function,fatigue and diarrhea in group A were worse than those in group B and C（P＜0.05).The symptoms of anorexia in group B were more severe than those in group A and group C（P＜0.05).In one year after operation,the scores of overall quality of life,physical function and emotional function in group C were better than those in group A and group B（P＜0.05),and the scores of role function in group C were better than those in group A（P＜0.05).The symptoms of fatigue and diarrhea in group A were more severe than those in group B and C（P＜0.05).The symptoms of anorexia in group B were more severe than those in group A and C（P＜0.05).QLQ-OG25 showed in six months after operation,the scores of dietary restriction,anxiety and diarrhea in group A were worse than those in group B and C（P＜0.05).The reflux symptoms in group B were more severe than those in group A and C（P＜0.05).In one year after operation,the symptoms of anxiety and diarrhea in group A were more severe than those in group B and C（P＜0.05).The reflux symptoms in group B were more severe than those in group A and C（P＜0.05).Conclusion:For patients with advanced Siewert type Ⅱ adenocarcinoma of the esophagogastric junction,the postoperative quality of life underwent double-channel anastomosis is better than that of traditional proximal gastrectomy and total gastrectomy.

References:

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Memo

Memo:
陕西省自然科学基金资助项目(编号：2014JQ4123)
Last Update: 2021-01-29