|Table of Contents|

Research progress on the relationship between tobacco use and bladder cancer and its mechanism

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2021 04
Page:
692-697
Research Field:
Publishing date:

Info

Title:
Research progress on the relationship between tobacco use and bladder cancer and its mechanism
Author(s):
WANG YiFENG LeiSHEN ShiyueSHI HuiXU WenrongLIANG Zhaofeng
School of Medicine,Jiangsu University,Jiangsu Zhenjiang 212013,China.
Keywords:
bladder cancertobacco useresearch progressmechanism
PACS:
R737.14
DOI:
10.3969/j.issn.1672-4992.2021.04.034
Abstract:
Bladder cancer is one of the most common malignant tumors of urinary system.Tobacco use is the main risk factor of bladder cancer,but the role of tobacco use in the occurrence and development of bladder cancer and its molecular mechanism have not been fully elucidated.Understanding the exact effect and mechanism of tobacco use in the occurrence and development of bladder cancer is very important for the prevention,early diagnosis and targeted treatment of bladder cancer.Our paper reviews the research progress of the relationship between tobacco use and bladder cancer in recent years and looks forward to the possible research direction and challenges in the future.The possible direction of research and the challenges in the future are also outlined.

References:

[1]CHANDRASEKAR T,EVANS CP.Autophagy and urothelial carcinoma of the bladder:A review[J].Investig Clin Urol,2016,57 Suppl 1:S89-S97.
[2]NCCN Guidelines Version 5.2018 bladder cancer[J].National Comprehensive Cancer Network:JNCCN,2018,16(9):1041-1053.
[3]陈晓芳,陈万青,周薇薇,等.2013年中国膀胱癌发病和死亡流行状况分析[J].中国肿瘤,2018,27(2):81-85. CHEN XF,CHEN WQ,ZHOU WW,et al.Analysis of the incidence and mortality of bladder cancer in China in 2013[J].Cancer in China,2018,27(2):81-85.
[4]温登瑰,张思维,郑荣寿,等.中国2009年膀胱癌发病和死亡资料分析[J].中国肿瘤,2013,22(7):521-527. WEN DG,ZHANG SW,ZHENG RS,et al.Data analysis of bladder cancer incidence and death in China in 2009[J].Cancer in China,2013,22(7):521-527.
[5]BESARATINIA A,TOMMASI S.Genotoxicity of tobacco smoke-derived aromatic amines and bladder cancer:Current state of knowledge and future research directions[J].FASEB J,2013,27:2090-2100.
[6]SOSNOWSKI R,PRZEWOZNIAK K.The role of the urologist in smoking cessation:Why is it important [J].Urol Oncol,2015,33:30-39.
[7]ALKAN O,ABAR H.Determination of factors influencing tobacco consumption in Turkey using categorical data analyses[J].Archives of Environmental & Occupational Health,2019:1-9.
[8]郝素华,康民瑞,王伟刚,等.专科医院医务人员吸烟状况及控烟知识态度行为调查[J].中国药物与临床,2014,8:1043-1045. HAO SH,KANG MR,WANG WG,et al.Investigation on smoking status and smoking control knowledge,attitude and behavior of medical staff in specialized hospitals[J].Chinese Medicine and Clinic,2014,8:1043-1045.
[9]GU D,KELLY TN,WU XC,et al.Mortality attributable to smoking in China[J].N Engl J Med,2009,360(2):150-159.
[10]LIANG ZF,WU R,XIE W,et al.Effects of curcumin on tobacco smoke-induced hepatic MAPK pathway activation and epithelial-mesenchymal transition in vivo[J].Phytother Res,2017,31:1230-1239.
[11]SHIHADEH A,SCHUBERT J,KLAIANY J,et al.Toxicant content,physical properties and biological activity of waterpipe tobacco smoke and its tobacco-free alternatives[J].Tob Control,2015,24 Suppl 1(Suppl 1):i22-i30.
[12]LU L,CHEN J,LI M,et al.β-carotene reverses tobacco smokeinduced gastric EMT via Notch pathway in vivo[J].Oncol Rep,2018,39:1867-1873.
[13]YU DX,GENG H,LIU ZQ,et al.Cigarette smoke induced urocystic epithelial mesenchymal transition via MAPK pathways[J].Oncotarget,2017,8:8791-8800.
[14]LIANG ZF,XIE W,WU R,et al.Inhibition of tobacco smoke-induced bladder MAPK activation and epithelial-mesenchymal transition in mice by curcumin[J].Int J Clin Exp Pathol,2015,8:4503-4513.
[15]LETASIOVA S,MEDVE'OVA A,SOVCIKOVA A,et al.Bladder cancer,a review of the environmental risk factors[J].Environ Health,2012,11 Suppl 1:S11.
[16]VAN OSCH FH,JOCHEMS SH,VAN SCHOOTEN FJ,et al.Quantified relations between exposure to tobacco smoking and bladder cancer risk;A meta-analysis of 89 observational studies[J].Int J Epidemiol,2016,45(3):570-857.
[17]SAMANIC C,KOGEVINAS M,DOSEMECI M,et al.Smoking and bladder cancer in Spain:Effects of tobacco type,timing,environmental tobacco smoke,and gender[J].Cancer Epidemiol Biomark Prev,2006,15(7):1348-1354.
[18]周玉华,秦国强,毕学成,等.被动吸烟与膀胱癌相关性的多中心病例对照研究[J].新医学,2014,45(5):300-303. ZHOU YH,QIN GQ,BI XC,et al.A multicenter case-control study on the relationship between passive smoking and bladder cancer[J].New Medicine,2014,45(5):300-303.
[19]JIN F,THAIPARAMBIL J,DONEPUDI SR,et al.Tobacco-specific carcinogens induce hypermethylation,DNA adducts,and DNA damage in bladder cancer[J].Cancer Prev Res (Phila),2017,10:588-597.
[20]BESARATINIA A,TOMMASI S.Genotoxicity of tobacco smoke-derived aromatic amines and bladder cancer:Current state of knowledge and future research directions[J].FASEB J,2013,27:2090-2100.
[21]LEE HW,WANG HT,WENG MW,et al.Cigarette side-stream smoke lung and bladder carcinogenesis:Inducing mutagenic acrolein-DNA adducts,inhibiting DNA repair and enhancing anchorage-independent-growth cell transformation[J].Oncotarget,2015,6:33226-33236.
[22]林云侨,李惠长.膀胱癌分子标志物诊断研究进展[J].医学综述,2010,16(02):216-218. LIN YQ,LI HC.Progress in molecular markers diagnosis of bladder cancer[J].Medical Recapitulate,2010,16(02):216-218.
[23]何苗.DNA甲基化与肿瘤[J].医学分子生物学杂志,2011,08(5):465-469. HE M.DNA methylation and tumor[J].Journal of Medical Molecular Biology,2011,08(5):465-469.
[24]薛艳凤,孔璟,陶剑.吸烟相关的DNA甲基化改变及疾病风险[J].国际遗传学杂志,2019,42(5):341-347. XUE YF,KONG J,TAO J.Smoking related DNA methylation changes and disease risk[J].International Journal of Genetics,2019,42(5):341-347.
[25]黄丽华,王君,金银龙.镉对DNA甲基化的影响[J].环境卫生学杂志,2014,4(2):200-202. HUANG LH,WANG J,JIN YL.Effect of cadmium on DNA methylation[J].Journal of Environmental Hygiene,2014,4(2):200-202.
[26]杨帆,纪卫东,张文娟.氯化镉诱导人膀胱上皮细胞恶性转化模型中METTL3的作用研究[C].北京:中国毒理学会,2018:72-73. YANG F,JI WD,ZHANG WJ.The role of mettl3 in the malignant transformation model of human bladder epithelial cells induced by cadmium chloride[C].Beijing:Chinese Society of Toxicology,2018:72-73.
[27]LIN RK,HSIEH YS,LIN P,et al.The tobacoo-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients[J].Clin Invest,2010,120(2):521-532.
[28]ROBINSON CM,NEARY R,LEVENDALE A,et al.Hypoxia-induced DNA hypermethylation in human pulmonary fibroblasts is associated with Thy-1 promoter methylation and the development of a pro-fibrotic phenotype[J].Respir Res,2012,13:74.
[29]李东,张旭,吴准,等.膀胱移行细胞癌中FHIT基因启动子甲基化及其表达的研究[J].临床泌尿外科杂志,2009,24(8):620-623. LI D,ZHANG X,WU Z,et al.Study of aberrant methylation of FHIT gene promoter and its expression in transitional cell carcinoma of the bladder [J].J Clini Urol,2009,24(8):620-623.
[30]WENG MW,HYUN-WOOK L,SUNG-HYUN P,et al.Aldehydes are the predominant forces inducing DNA damage and inhibiting DNA repair in tobacco smoke carcinogenesis[J].Proceedings of the National Academy of Sciences,2018,115(27):E6152-E6161.
[31]BELLAMRI M,YAO L,BONALA R,et al.Bioactivation of the tobacoo carcinogens 4-aminobipheny1(4-ABP) and 2-amino-9H-pyrido[2,3-b]indole(AαC) in human bladder RT4 cells[J].Arch Toxicol,2019,93(7):1893-1902.
[32] ALEXANDROV LB,JU YS,HAASE K,et al.Mutational signatures associated with tobacco smoking in human cancer[J].Science,2016,354(6312):618-622.
[33] FAN TJ,SUN GH,ZHAO LJ,et al.Metabolic activation and carcinogenesis of tobacco-specific nitrosamine N'-nitrosonornicotine (NNN):A density function theory and molecular docking study[J].International Journal of Environmental Research and Public Health,2019,16(2):178.
[34]SUZUKI S,COHEN SM,AMOLD LL,et al.Cotinine,a major nicotine metabolite,induces cell proliferation on urothelium in vitro and in vivo[J].Toxicology,2020,429:152325.
[35]YUGE L,KIKUCHI E,HAGIWARA M,et al.Nicotine induces tumor growth and chemoresistance through activation of the PI3K/Akt/mTOR pathway in bladder cancer[J].Mol Cancer Ther,2015,14(9):2112-2120.
[36]ZHOU Q,JIN P,LIU J,et al.HER2 and Src co-regulate proliferation,migration and transformation by downstream signaling pathways in arsenite-treated human uroepithelial cells[J].Metallomics,2018,10(8):1141-1159.
[37]JIN P,LIU J,WANG X,et al.HER2 activation factors in arsenite-exposed bladder epithelial cells[J].Toxicol Sci,2018,166(2):354-369.
[38]李媛媛,姜玉峰,慕晓玲.砷致癌抗癌机制与MAPK通路的研究进展[J].农垦医学,2010,32(004):343-346. LI YY,JIANG YF,MU XL.Research progress on arsenic carcinogenesis and anticancer mechanism and MAPK pathway [J].Agricultural Reclamation Medicine,2010,32(004):343-346.
[39]SUN X,ZHANG T,DENG Q,et al.Benzidine induces epithelial-mesenchymal transition of human bladder cancer cells through activation of ERK5 pathway[J].Moleculer Cells,2018,41(3):188-197.
[40] LIANG ZF,LU L,MAO J,et al.Curcumin reversed chronic tobacco smoke exposure induced urocystic EMT and acquisition of cancer stem cells properties via Wnt/β-catenin[J].Cell Death and Disease,2017,8(10):e3066.
[41]梁照锋,陶海,郭文浩,等.香烟烟雾促进膀胱癌干细胞的自我更新和干性基因的表达[J].江苏大学学报(医学版),2019,29(3):205-207. LIANG ZF,TAO H,GUO WH,et al.Cigarette smoke promotes the self-renewal of bladder cancer stem cells and the expression of dry genes [J].Journal of Jiangsu University (Medical Edition),2019,29(3):205-207.
[42] QIAN W,KONG X,ZHANG T,et al.Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway[J].Oncogenesis,2018,7(3):24.

Memo

Memo:
江苏大学“优秀青年骨干教师培育计划”(编号:5521280013);江苏省高等学校大学生创新创业训练计划项目(编号:201910299176Y);江苏大学科研立项(编号:18A451,18A474)
Last Update: 1900-01-01