|Table of Contents|

The clinical application of positron emission tomography in the diagnosis of cardiac malignant tumors

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2021 04
Page:
656-659
Research Field:
Publishing date:

Info

Title:
The clinical application of positron emission tomography in the diagnosis of cardiac malignant tumors
Author(s):
CHEN Lanlan; HAO Shanhu; ZHANG Guoxu
Department of Nuclear Medicine,the General Hospital of Northern Theater Command,Liaoning Shenyang 110016,China.
Keywords:
cardiac neoplasms; positron emission tomography; deoxyglucose; tomography; X-ray computed
PACS:
R732.1
DOI:
10.3969/j.issn.1672-4992.2021.04.024
Abstract:
Objective：To investigate the clinical value of positron emission tomography (PET/CT) in the diagnosis of cardiac tumors.Methods:The PET/CT imaging of 23 patients with cardiac tumors who underwent PET/CT examination from January 2011 to December 2018 was restrospectively analyzed.The diagnostic was based on postoperative pathological findings and clinical follow-up results.The PET/CT diagnostic efficacy of cardiac tumor was evaluated.The SUVmax of benign and malignant tumors was compared with the definite diagnosis,and the data was analyzed by two-sample t-test.Results:Among the 23 patients with cardiac tumors,19 were malignant tumors,6 were primary malignant tumors,13 were metastatic tumors,and 4 were benign cases.The sensitivity,specificity and accuracy of PET/CT imaging in benign and malignant neoplasms were 89.5%(17/19),75.0%(3/4),and 87.0%(20/23),respectively.The average SUVmax of malignant tumors was 14.5±9.7.The SUVmax of benign tumors was 3.0±2.4.There was a significant difference between the two groups (t=-1.95,P＜0.05).PET/CT imaging of malignant tumors found that 16 people with multiple parts and multiple organ metastases and changed clinical staging and therapeutic schedule.Conclusion:PET/CT imaging has a high sensitivity and specificity for the diagnosis of cardiac malignant tumors which can help to differentiate the benign and malignant lesions cardiac occupying lesions,and has great guidance for the clinical staging and treatment of tumors.

References:

［1］ FROM AM,MALESZEWSKI JJ,RIHAL CS．Current status of endomyocardial biopsy［J］.Mayo Clin Proc,2011,86:1095-1102.
［2］ EKMEKTZOGLOU KA,SAMELIS GF,XAMTHOS T.Heart and tumors:Location,metastasis,clinical manifestations,diagnostic approaches and therapeutic considerations［J］.Cardiovasc Med (Hagerstown),2008,9:769-777.
［3］ LAM KY,DICKENS P,CHAN AC.Tumors of the heart,a 20-year experirnce with a review of 12,485 consecutive autopsies［J］.Arch Pathol Lab Med,1993,117(10):1027-1031.
［4］ BUSSANI R,DE-GIORGIO F,ABBATE A,et al.Cardiac metastases［J］.Clin Pathol,2007,60(1):27-34.
［5］ RAHBAR K,SEIFARTH H,SCHAFES M,et al.Differentiation of malignant and benign cardiac tumors using 18F-FDG PET/CT［J］.Nucl Med,2012,53(6):856-863.
［6］ WEBER WA,GROSU AL,CZEMIN J.Technology insight:Advances in molecular imaging and an appraisal of PET/CT scaning［J］.Nat Clin Pract Oncol,2008,5(3):160-170.
［7］ 赵世俊，吴宁，郑容，等.18F-FDG PET/CT SUVmax与非小细胞癌手术患者预后的关系［J］.癌症进展，2014,12（2）：205-211. ZHAO SJ,WU N,ZHENG R,et al.Prognostic significance of SUVmax on 18FDG-PET/CT in patients with surgically resectd non-small cell lung cancer［J］.Oncology Progress,2014,12(2):205-211.
［8］ 孙龙，江茂倩，赵龙，等.18F-FDG PET/CT在心脏肿瘤的临床应用［J］.中华核医学与分子影像杂志，2013,33（3）：175-178. SUN L,JANG MQ,ZHAO L,et al.Clinical application of 18F-FDG PET/CT for cardiac neoplasm diagnisis［J］.Chinese Joumal of Nuclear Medicine,2013,33(3):175-178.
［9］ 孙晓昕，何作祥，张晓丽，等.18F-FDG PET/CT在心脏占位性病变良恶性鉴别诊断中的应用［J］.中华核医学与分子影像杂志，2015,35（2）：85-87. SUN XX,HE ZX,ZHANG XL,et al.Diagnostic value of 18F-FDG PET/CT in differentiating the cardiac benign from malignant lesions［J］.Chinese Joumal of Nuclear Medicine,2015,35（2）：85-87.
［10］ 高平，王茜.18F-FDG PET/CT在心脏肿瘤的鉴别诊断价值［J］.中国医学影像学杂志，2016,24（10）:771-774. GAO P,WANG Q.Differential diagnosis of 18F-FDG PET/CT in benign and malignant cardiac tumor［J］.Chinese Joumal of Nuclear Medicine,2016,24(10):771-774.
［11］ JELLIS C,DOYLE J,SUTHERLAND T,et al.Cardiac epithelioid leiomyosarcoma and the role of cardiac imaging in the differentiation of intracardiac masses［J］.Clin Cardiol,2010,33:E6-9.
［12］ LEJA MJ,SHAH DJ,REARDON MJ.Primary cardiac tumors［J］.Tex Heart Inst,2011,38:261-262.
［13］ JULIAN A,WAGNER T,YSEBAERT L,et al.FDG PET/CT leads to the detection of metastatic involvement of the heart in non-Hodgkin's Iymphpma［J］.Eur J Nucl Med Mol Imaging,2011,38:1174.
［14］ CASTILLO JG,SILVAY G.Characterization and management of cardiac tumors［J］.Semin Cardiothorac Vasc Anesth,2010,14:6-20.
［15］ CATFORD SR,LEE KT,PACE MD,et al.Cardiac metastasis from thyroid carcinoma［J］.Thyroid,2011,21:855-866.
［16］ KASSOP D,DONOVAN MS,CHEEZUM MK,et al.Cardiac masses on cardiac CT:a review［J］.Curr Cardiovasc Imaging Rep,2014,7:9281.
［17］ 张智旸，高鑫，白春梅，等. 心脏原发性血管肉瘤16例的临床影像特征及预后［J］.中华心血管杂志，2019,47（9）：731-736. ZHANG ZY,GAO X,BAI CM,et al.Clinical and radiologic characteristics as well as outcomes of patients with primary cardiac angiosarcoma［J］.Chinese Iournal of Cardiology,2019,47（9）：731-736.
［18］ 刘磊，周力，陈晖，等.PET/CT在心血管疾病中的应用［J］.医学综述，2019，25(7):1394-1398. LIU L,ZHOU L,CHEN H,et al.Application of positron emission tomography/compueed tomography in cardiovascular diseases［J］.Medical Recapitulate,2019，25(7):1394-1398.
［19］ MAURER AH,BURSHTEYN M,ADLER LP,et al.How to differentiate benign versus malignant cardiac and paracardiac 18F FDG uptake at oncologic PET/CT［J］.Radiographics,2011,31(5):1287-1305.

Memo

Memo:
辽宁省科学技术计划项目（编号：2012225019）
Last Update: 1900-01-01