|Table of Contents|

Research progress of effect of microRNA regulation of EMT on invasion and metastasis of cervical cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2021 02
Page:
341-345
Research Field:
Publishing date:

Info

Title:
Research progress of effect of microRNA regulation of EMT on invasion and metastasis of cervical cancer
Author(s):
PEI Xiangchun; WANG Zhilian
Shanxi Medical University,Shanxi Taiyuan 030000,China.
Keywords:
microRNA; EMT; cervical cancer
PACS:
R737.33
DOI:
10.3969/j.issn.1672-4992.2021.02.035
Abstract:
Cervical cancer is a common malignancy in women worldwide.The overall prognosis for cervical cancer remains poor due to metastasis or recurrence,especially in patients with advanced cancer.Metastasis accounts for about 90 percent of all cancer-related deaths.Therefore,identifying the causes and potential markers of metastasis is of great significance for promoting early diagnosis,predicting prognosis and developing new treatment strategies for cervical cancer.During the development and progression of cervical cancer,many microRNAs (miRNAs) have been shown to be significantly maladjusted.There is increasing evidence that miRNAs can effectively regulate the process of epithelial-mesenchymal transition (EMT),which includes control of EMT signaling pathways and direct targeting of EMT transcription factors to regulate the invasion and metastasis of cancer cells.This summary will briefly elucidate the effect of miRNA regulation of EMT on the invasion and metastasis of cervical cancer.

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Memo

Memo:
山西省卫生计生委科研课题（编号：201601046）；山西医科大学第二医院博士基金（编号：201701-8）
Last Update: 1900-01-01