|Table of Contents|

Research of quantitative evaluation of radiotherapy for rectal cancer based on PQM script

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2021 02
Page:
331-334
Research Field:
Publishing date:

Info

Title:
Research of quantitative evaluation of radiotherapy for rectal cancer based on PQM script
Author(s):
HE Ruimin1; YANG Xiaoyu2; LI Shuzhou2; YANG Zhen2; CAO Ying2; HE Qiudong1; XIAO Ruobing1
1.Department of Radiotherapy,the Second Affiliated Hospital,University of South China,Hunan Hengyang 421400,China;2.Radiotherapy Center，Department of Oncology,Xiangya Hospital,Central South University,Hunan Changsha 410005,China.
Keywords:
C#; plan quality metrics; rectal cancer; Plan IQ
PACS:
R730.55
DOI:
10.3969/j.issn.1672-4992.2021.02.032
Abstract:
Objective:To build a plan quality metrics(PQM)assessment script to quantify the treatment plan and verify the feasibility of the script.Methods:A plan quality metrics with 18 submetrics for rectal cancer was established to build a assessment script in the Visual Studio with C#.Treatment plans with different delivery techniques was evaluated and scored by the script program and Plan IQ software respectively.First,the difference between the two evaluation methods was analyzed,and then the scores of the two delivery techniques were compared to verify the feasibility of the script.Results:In Script group and Plan IQ group,the target scores of the VMAT group and the IMRT group were(73.2±16.6)scores,(56.8±14.9)scores and（70.7±19.3)scores，(63.1±11.5）scores,and the difference was statistically significant(P＜0.05).Scores of OAR were(91.9±3.2)scores,(80.4±8.5)scores and（89.9±5.1)scores，(75.1±11.0）scores,and the difference was statistically significant(P＜0.05).Total scores were(84.1±8.1)scores,(70.2±10.0)scores and(84.6±5.9)scores,(71.8±10.0)scores,and the difference was statistically significant(P＜0.05).In the comparative analysis of the data,the data outside the consistency interval accounted for <5% of the total.Conclusion:The script can evaluate the quality of treatment plan effectively and objectively,and can be used as the evaluation application for treatment planning system.

References:

［1］ 吴骏翔,康盛伟,王培,等.宫颈癌术后放疗中自动计划与人工计划的剂量学比较［J］.中华放射医学与防护杂志,2018,38(1):26-31. WU Junxiang,KANG Shengwei,WANG Pei,et al.Dosimetric comparison between automated and manual volumetric modulated arc therapy planning for postoperative cervical cancer［J］.Chin J Radiol Med Prot,2018,38(1):26-31.
[2] STASI M,BRESCIANI S,MIRANTI A,et al.Pretreatment patient-specific IMRT quality assurance:A correlation study between gamma index and patient clinical dose volume histogram［J］.Med Phys,2012,39(12):7626-7634.
[3] BOWERS M,ROBERTSON S,MOORE J,et al.A multi-institutional plan quality checking tool built on oncospace:A shared radiation oncology database system［J］.Med Phys,2016,43(6):3366-3366.
[4] FREEMAN M,CHANYAVANICH V,DAS S,et al.A linear metric of knowledge-based IMRT treatment plan quality for the prostate［J］.Med Phys,2010,37(6):3214-3214.
[5] RUAN D,SHAO W,DEMARCO J,et al.Evolving treatment plan quality criteria from institution-specific experience［J］.Med Phys,2012,39(5):2708-2712.
[6] CLARKE S,GOODWORTH J,WESTHUYZEN J,et al.Software-based evaluation of a class solution for prostate IMRT planning［J］.Rep Pract Oncol Radiother,2017,22(6):441-449.
[7] BIAND J,AITMAN D.Statistical methods for assessing agreement between two methods of clinical measurement［J］.Lancet,1986,327(8476):307-310.
[8] NELMS B,ROBINSON G,MARKHAM J,et al.Variation in external beam treatment plan quality:An inter-institutional study of planners and planning systems［J］.Pract Radiat Oncol,2012,2(4):296-305.
[9] HOOPES D,JOHNSTONE P,CHAPIN P,et al.Practice patterns for peer review in radiation oncology［J］.Pract Radiat Oncol,2015,5(1):32-38.
[10] JIANG Z,JACKIE W,YAORONG G,Knowledge-based statistical inference method for plan quality metrics［J］.Technol Cancer Res Treat,2019,18：1-10.
[11] RAVINDRA Y,MADHUI K,JIN S,et al.Evaluating which plan quality metrics are appropriate for use in lung SBRT［J］.Br J Radiol,2018(91)：1083-1091.
[12] 夏文龙,陈波,黄鹏,等.基于计划质量度量(PQM)量化比较有无均整器模式下肝癌容积旋转调强放疗计划［J］.中华放射医学与防护杂志,2018,38(9):680-683. XIA WL,CHEN B,HUANG P，et al.Quantitative comparison of volumetric modulated arc therapyplans for liver cancer using flatting filter-free and flatting filter modes based on plan quality metrics(PQM)［J］.Chin J Radiol Med Prot,2018,38(9):680-683.
[13] OTTO K.Volumetric modulated arc therapy:IMRT in a single gantry arc［J］.Med Phys,2008,35(1):310-317.
[14] KNAPP P,EVA B,RESEIGH G,et al.The role of volumetric modulated arc therapy (VMAT) in gynaecological radiation therapy:A dosimetric comparison of intensity modulated radiation therapy versus VMAT［J］.J Med Radiat Sci,2019,66(1)：44-53.
[15] 周云泷,许敬辉,杨涛，等.早期非小细胞肺癌治疗计划中IMRT与VMAT单双拉弧的剂量学对比［J］.现代肿瘤医学,2019,27(04):646-649. ZHOU YL,XU JH,YANG T,et al.Dosimetry comparison of IMRT and VMAT single and double arcing in the treatment of lung cancer［J］.Modern Oncology,2019,27(04):646-649.

Memo

Memo:
National Natural Science Foundation of China(No.61906215）；国家自然科学基金青年科学基金项目(编号：61906215)
Last Update: 1900-01-01