|Table of Contents|

Three cases of primary tracheal B cell lymphoma and literature review

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2021 01
Page:
127-132
Research Field:
Publishing date:

Info

Title:
Three cases of primary tracheal B cell lymphoma and literature review
Author(s):
XU Ling; LYU Liping
Interventional Pulmonology Department，Anhui Chest Hospital，Anhui Hefei 230000，China.
Keywords:
lymphoma; trachea; surgery; radiotherapy; chemotherapy; endoscopic therapy
PACS:
R733
DOI:
10.3969/j.issn.1672-4992.2021.01.029
Abstract:
Objective：To explore the optimal treatment mode for primary tracheal B cell lymphoma according to the review and analysis of 32 cases.Methods：Three patients with confirmed primary tracheobronchial lymphoma of Anhui Chest Hospital from November 2016 to May 2017 were analyzed retrospectively，and 29 similar cases reported in published papers were also collected.The clinical symptoms，imaging features，treatment methods and follow-up time were analyzed to invest the best treatment model for B cell lymphoma.Results：In 32 patients，the age was from 31 to 83 years old.12 patients were male，and 20 patients were female.Most patients had non-typical early symptoms，like cough and asthma.Some patients had emergency visits due to dyspnea.The single or multiple nodules were further examined under tracheoscope，and the pathological pattern was reported as B cell lymphoma.The treatments of B cell lymphoma were different，like surgery，radiotherapy，chemotherapy，endoscopic therapy，and the combination of those methods.Conclusion：The curative effect of B cell lymphoma is better in general，and the patients usually have long lifetimes.With the development of the tracheoscope technique，the author thinks that the combination of chemotherapy and endoscopic therapy is a best treatment pattern，which has a curative effect with slight side effects.However，there are still need more date to support this opinion.

References:

［1］HOERBELT R，PADBERG W.Primary tracheal tumors of the neck and mediastinum：resection and reconstruction procedures［J］.Chirurgery，2011，82(2)：125-133.
［2］WIGGINS J，SHEFIELD E，GREEN M.Primary B cell malignant lymphoma of the trachea［J］.Thorax，1988，43(6)：497-498.
［3］陈镇华，唐惟瑜.原发性气管恶性淋巴瘤1例［J］.肿瘤，1992，12（02）：59. CHEN ZH，TANG WY.Primary malignant lymphoma of the trachea：A case report［J］.Tumor，1992，12（02）：59.
［4］KAPLAN MA，PETTIT CL，ZUKERBERG LR，et al.Primary lymphoma of the trachea with morphologic and immunophenotypic characteristics of low-grade B-cell lymphoma of mucosal associated lymphoid tissue［J］.Am J Surg Pathol，1992，16(1)：71.
［5］KOBAYASHI H，NEMOTO Y，NAMIKI K，et al.Primary malignant lymphoma of the trachea and subglottic region［J］.Inter Med，1992，31(5)：655.
［6］TSURUTANI J，KINOSHITA A，KAIDA H，et al.Bronchoscopic therapy for mucosa-associated lymphoid tissue lymphoma of the trachea［J］.Inter Med，1999，38(3)：276.
［7］SUZUKI T，AKIZAWA T，SUZUKI H，et al.Primary tracheal mucosa-associated lymphoid tissue lymphoma accompanying lung cancer：Common tumor genesis or coincidental coexistence［J］.Jpn J Thorac Cardiovasc Surg，2000，48(12)：817.
［8］徐秋芬，高明哲，梁瑛.气管内非霍奇金淋巴瘤一例［J］.中华内科杂志，2002，9（12）：848. XU QF，GAO MZ，LIANG Y.A case of endotracheal non-Hodgkin's lymphoma［J］.Chinese Journal of Internal Medicine，2002，9（12）：848.
［9］石建光，励新健，蓝之源.原发气管非霍奇金淋巴瘤1例［J］.中华胸心血管外科杂志，2003，19（6）：384. SHI JG，LI XJ，LAN ZY.A case of primary non-Hodgkin's lymphoma of trachea［J］.Chinese Journal of Thoracic and Cardiovascular Surgery，2003，19（6）：384.
［10］王勇，李玉，李建华，等.原发气管B细胞淋巴瘤1例［J］.中华结核和呼吸杂志，2005，28（10）：732. WANG Y，LI Y，LI JH,et al.A case of primary B cell lymphoma of trachea［J］.Chinese Journal of Tuberculosis and Respiratory Diseases，2005，28（10）：732.
［11］OKUBO K，MIYAMOTO N，KOMAKI C,et al.Primary mucosa-associated lymphoid tissue(MALT) lymphoma of the trachea：A case of surgical resection and long term survival［J］.Thorax，2005，60(1)：82.
［12］ANDRATSCHKE M，STELTER K，IHRLER S，et al.Subglotic tracheal stenosis as primary manifestation of a marginal zone B-cell lymphoma of the larynx［J］.In Vivo，2005，19(3)：547-550.
［13］HASHEMI SM，HEITBRINK MA，JIWA M，et al.A patient with endobronchial BALT lymphoma successfully treated with radiotherapy［J］.Resp Med，2007，101(10)：2227-2229.
［14］GARCíA-GARCíA J，LóPEZ GARCíA F，CARATALá TOREGROSA J，et al.Tracheal MALT lymphoma：First case report from Spain［J］.Med Clin(Barc)，2008，131(12)：478-479.
［15］KANG JY，PARK HJ，LEE KY，et al.Extranodal marginal zone lymphoma occurring along the trachea and central air way［J］.Yonsei Med J，2008，49(5)：860.
［16］MIRA-AVENDANO I，CUMBO-NACHELI G，PARAMBIL J.Mucosa-associated lymphoid tissue lymphoma of the trachea［J］.J Bronchology Interv Pulmonol，2012，19(1)：44-46.
［17］MAGLIARI ME，AQUINO RT，GONALVES AL，et al.Mucosa-associated lymphoid tissue lymphoma of the trachea：Case report［J］.Sao Paulo Med J，2012，130(2)：126-129.
［18］丁娟娟，陈卓昌，石曼丽.原发气管黏膜相关性淋巴组织型淋巴瘤1例临床分析［J］.郑州大学学报：医学版，2012，47(2)：273-275. DING JJ，CHEN ZC，SHI ML.Primary tracheal mucosa associated lymphoid tissue lymphoma：A case report［J］.Journal of Zhengzhou University(Medical Sciences)，2012，47(2)：273-275.
［19］YOON RG，KIM MY，SONG JW，et al.Primary endobronchial marginal zone B-cell lymphoma of bronchus-associated lymphoid tissue：CT findings in 7 patients［J］.Korean J Radiol，2013，14(2)：366-374.
［20］MIZUNOA S，OTA S，TANAKA T，et al.Primary tracheal malignant lymphoma detected during a regular checkup in an asbestos dust-exposed smoker［J］.Acta Med Okayama，2014，68(3)：177-181.
［21］王晓野，初建国，孙博，等.原发性气管非霍奇金淋巴瘤1例［J］.中国医学影像技术，2015，31（7）：1032. WANG XY，CHU JG，SUN B，et al.Primary non-Hodgkin's lymphoma of the trachea：a case report［J］.Chinese Journal of Medical Imaging Technology，2015，31（7）：1032.
［22］韩磊，王芮琦，李杨，等.原发气管黏膜相关淋巴组织淋巴瘤1例［J］.中国老年学杂志，2015，35（3）：791-792. HAN L，WANG RQ，LI Y，et al.Primary tracheal mucosa associated lymphoid tissue lymphoma：A case report［J］.Chin J Gerontol，2015，35（3）：791-792.
［23］王卢莎，韩睿宁，张萌，等.声门下及气管原发性非霍奇金淋巴瘤1例［J］.山东大学耳鼻喉眼学报，2016，30（5）：125-126. WANG LS，HAN RN，ZHANG M，et al.A case of primary non-Hodgkin's lymphoma under the glottis and trachea［J］.Journal of Otolaryngology and Ophthalmology of Shandong University，2016，30（5）：125-126.
［24］吕品，尹金植，刘晶，等.纤维支气管镜下氩等离子凝固及冷冻治疗气管黏膜相关淋巴组织淋巴瘤1例及文献复习［J］.吉林大学学报（医学版），2016，42（1）：152-154. LYU P，YIN JZ，LIU J，et al.Treatment of tracheal mucosa associated lymphoid tissue lymphoma with argon plasma coagulation and cryotherapy under fiberbronchoscope：A case report and literature review［J］.Journal of Jilin University(Medicine Edition)，2016，42（1）：152-154.
［25］尹雯，袁明丽，胡轶，等.原发气管黏膜相关淋巴组织淋巴瘤1例及文献回顾［J］.华中科技大学学报（医学版），2017，46（2）：227-230. YIN W，YUAN ML，HU Y，et al.Primary tracheal mucosa associated lymphoid tissue lymphoma：A case report and literature review［J］.Acta Medicinae Universitatis Scientiae et Technologiae Huazhong，2017，46（2）：227-230.
［26］DAISUKE M，CHIHIRO A，KEN S，et al.Multiple mucosa-associated lymphoid tissue lymphoma of the trachea［J］.Internal Medicine，2017，56(21)：2907-2911.
［27］李梦杰，刘鹏，施淑静，等.气管黏膜相关淋巴组织结外边缘区B细胞淋巴瘤1例报告［J］.临床肺科杂志，2019，24(12)：2313-2314. LI MJ，LIU P，SHI SJ，et al.A case of B-cell lymphoma in the extranodal margin of tracheal mucosa associated lymphoid tissue［J］.Journal of Clinical Pulmonary Medicine，2019，24(12)：2313-2314.
［28］LI Y，JIANG J，FELIX JF HERTH，et al.Primary tracheal mucosa-associated lymphoid tissue lymphoma treated with a water-jet hybrid knife：a case report［J］.Respiration，2018，97(2)：1-5.
［29］AHN JH，CHUNG JH，SHIN KC，et al.Mucosa-associated lymphoid tissue lymphoma of the trachea associated with idiopathic pulmonary fibrosis：A case report and literature review［J］.Medicine，2018，97(20)：e10727.
［30］杨霞，阮玉英，黎秋连，等.原发气管支气管淋巴瘤两例报告并文献复习［J］.中国呼吸与危重监护杂志，2017，16（3）：255-259. YANG X，RUAN YY，LI QL，et al.Primary tracheobronchial lymphoma：Two cases report and literature review［J］.Chinese Journal of Respiratory and Critical Care Medicine，2017，16（3）：255-259.
［31］WANG AY，WANG JT，SHEN Y，et al.Relapse of non-Hodgkin's lymphoma involving the trachea：Acute subglottic obstruction［J］.Case Rep Otolaryngol，2014，2014：230682.
［32］ZINZANI PL,MAGAGNOLI M,GALIENI P,et al.Nongastrointestinal low-grade mucosa-associated lymphoid tissue lymphoma:Analysis of 75 patients［J］.Journal of Clinical Oncology,1999,17(4):1254-1258.
［33］GUTIéRREZ L，FERNANDEZ L，SUA LF.Malignant obstruction of the central airway by an EBV(+) diffuse large B-cell lymphoma：An unusual presentation：track：bronchoscopy［J］.J Thorac Oncol，2016，11(10S)：S228-S231.

Memo

Memo:
中华国际医学交流基金会科研专项基金项目（编号：Z-2014-06-18381）
Last Update: 2020-11-30