|Table of Contents|

Application of nano-carbon tracer in the breast mastoscopic axillary lymph node dissection

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2021 01
Page:
69-72
Research Field:
Publishing date:

Info

Title:
Application of nano-carbon tracer in the breast mastoscopic axillary lymph node dissection
Author(s):
WU WeiFEI ZheweiLU PingCHEN Haiqun
Department of Thyroid and Breast Surgery,Chongming Branch,Xinhua Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 202150,China.
Keywords:
nano-carbonbreast cancerbreast mastoscopicaxillary lymph node dissectionsentinel lymph node
PACS:
R737.9
DOI:
10.3969/j.issn.1672-4992.2021.01.015
Abstract:
Objective:To investigate the application value of nano-carbon tracer technology in breast mastoscopic axillary lymph node dissection.Methods:A total of 60 patients with cN0-1 breast cancer who were hospitalized in our hospital from June 2015 to June 2018 were enrolled.The patients were divided into the nano-carbon-assisted mastoscopic group(the observation group) and conventional mastoscopic group(control group) randomly.Each group had 30 cases,and we analyzed the detection results of sentinel lymph nodes in patients with nano-carbon tracers,and compared the two groups of lymph node dissection,operation time and incidence of postoperative complications.Results:The detection rate of nano-carbon tracer assisted mammoscopic axillary lymph node dissection was 100%.The sensitivity was 92.31%.The false negative rate was 7.69%,and the accuracy was 96.67%.In terms of the total number of lymph nodes and micro-lymph nodes,the observation group was significantly higher than the control group(P<0.05),but there was no significant difference between the two groups in the operation time and the incidence of postoperative complications(P>0.05).Conclusion:Compared with conventional mastoscopic axillary lymph node dissection,nano-carbon tracers can increase the detection rate of lymph nodes and the positive detection rate of metastatic lymph nodes,especially the detection rate of micro-lymph nodes,and would not increase the extra operation time and incidence of postoperative complications.

References:

[1]DE BONIFACE J,FRISELL J,ANDERSSON Y,et al.Survival and axillary recurrence following sentinel node-positive breast cancer without completion axillary lymph node dissection:The randomized controlled SENOMAC trial[J].BMC Cancer,2017,17(1):379.
[2]YUAN H,XIE D,XIAO X,et al.The clinical application of mastectomy with single incision followed by immediate laparoscopic-assisted breast reconstruction with latissimus dorsi muscle flap[J].Surg Innov,2017,24(4):349-352.
[3]ROSSI EC,KOWALSKI LD,SCALICI J,et al.A comparison of sentinel lymph node biopsy to lymphadenectomy for endometrial cancer staging(FIRES trial):A multicentre,prospective,cohort study[J].Lancet Oncol,2017,18(3):384-392.
[4]WANG L,YANG D,LV JY,et al.Application of carbon nanoparticles in lymph node dissection and parathyroid protection during thyroid cancer surgeries:A systematic review and Meta-analysis[J].Onco Targets Ther,2017,10:1247-1260.
[5]WU QF,YU YH,ZHU X,et al.Development of video-assisted breast cancer surgery:Initial experience with a novel method for creating working space without prior liposuction[J].Mol Clin Oncol,2017,7(1):32-38.
[6]GRADISHAR WJ,ANDERSON BO,BALASSANIAN R,et al.NCCN guidelines insights:breast cancer[J].J Natl Compr Canc Netw,2017,15(4):433-451.
[7]颜博,葛洁,张斌,等.纳米碳在乳腺癌前哨淋巴结活检中的临床应用[J].中国肿瘤临床,2011,38(21):1335-1337. YAN Bo,GE Jie,ZHANG Bin,et al.Application of a carbon nanoparticle suspension injection into the mammary gland in the sentinel lymph node biopsy for breast cancer[J].Chin J Clin Oncol,2011,38(21):1335-1337.
[8]LIU XB,ZHOU YA.Clinical analysis of 50 cases of breast cancer treated with minimally invasive mammoscopic surgery[J].Chinese Journal of General Surgery(E-edition),2017,11(6):531-533.
[9]CUI L,RAO J.Semiconducting polymer nanoparticles as photoacoustic molecular imaging probes[J].Wiley Interdiscip Rev Nanomed Nanobiotechno,2017,9(2):1-12.
[10]骆成玉.乳腔镜腋窝淋巴结清扫的标准化手术技术[J].中国微创外科杂志,2006,6(05):341-342. LUO CY.Standardized surgical technique for breast axillary lymph node dissection[J].Chinese Journal of Minimally Invasive Surgery,2006,6(05):341-342.
[11]ZHANG P,LUO Y,DENG J,et al.Endoscopic axillary lymphadenectomy combined with laparoscopically harvested pedicled omentum for immediate breast reconstruction[J].Surg Endosc,2015,29(6):1376-1383.
[12]FANG J,MA L,ZHANG YH,et al.Endoscopic sentinel lymph node biopsy and endoscopic axillary lymphadenectomy without liposuction in patients with early stage breast cancer[J].Surg Oncol,2017,26(4):338-344.
[13]JAYNE D,PIGAZZI A,MARSHALL H,et al.Effect of robotic-assisted vs conventional laparoscopic surgery on risk of conversion to open laparotomy among patients undergoing resection for rectal cancer:The ROLARR randomized clinical tria[J].JAMA,2017,318(16):1569-1580.
[14]LYMAN GH,SOMERFIELD MR,GIULIANO AE.Sentinel lymph node biopsy for patients with early-stage breast cancer:2016 american society of clinical oncology clinical practice guideline update summary[J].J Oncol Pract,2017,13(3):196-198.
[15]EHTESHAMI BEJNORDI B,VETA M,JOHANNES VAN DIEST P,et al.Diagnostic assessment of deep learning algorithms for detection of lymph node metastases in women with breast cancer[J].JAMA,2017,318(22):2199-2210.
[16]LONG M,LUO D,DIAO F,et al.A carbon nanoparticle lymphatic tracer protected parathyroid glands during radical thyroidectomy for papillary thyroid non-microcarcinoma[J].Surg Innov,2017,24(1):29-34.
[17]LIU L,ZHU J,LU C,et al.The role of nanocarbon lymphatic tracer in thoraco-laparoscopic esophagectomy[J].Minerva Chir,2017,72(6):475-482.
[18]YANG SX,WEI WS,JIANG QH,et al.Analysis of 246 sentinel lymph node biopsies of patients with clinical primary breast cancer by application of carbon nanoparticle suspension[J].J Obstet Gynaecol Res,2018,44(6):1150-1157.
[19]张月,王耀一,孙光源,等.腔镜下前哨淋巴结活检及腋窝淋巴结清扫在早期乳腺癌手术中的应用[J].实用癌症杂志,2015,30(9):1335-1338. ZHANG Y,WANG YY,SUN GY,et al.Application of sentinel lymph node biopsy and axillary lymph node dissection in early breast cancer surgery[J].Journal of Practical Cancer,2015,30(9):1335-1338.
[20]BIRD B,MILJKOVIC M,ROMEO MJ,et al.Infrared micro-spectral imaging:Distinction of tissue types in axillary lymph node histology[J].BMC Clin Pathol,2008(8):8.

Memo

Memo:
崇明县科学技术发展资金项目(编号:CKY2015-04)
Last Update: 2020-11-30