|Table of Contents|

Progress on functions of exosomes in a tumor microenvironment

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2020 03
Page:
504-507
Research Field:
Publishing date:

Info

Title:
Progress on functions of exosomes in a tumor microenvironment
Author(s):
Wang HaofeiWei Minjie
School of Pharmacy,China Medical University,Liaoning Shenyang 110122,China.
Keywords:
exosometumor microenvironmentextracellular vesicles
PACS:
R730.2
DOI:
10.3969/j.issn.1672-4992.2020.03.037
Abstract:
Extracellular vesicles have been considered as an important way of intercellular communication,especially the functions of exosomes in physiological and pathological process has been paid more and more attention by researchers.In the tumor microenvironment,tumor cells,immune cells and stromal cells are the main sources of exosomes.A large number of bioactive molecules encapsulated in exosomes play an important role in phenotypic differentiation,physiological function and metabolic status of downstream target cells.It is of great significance to explore the regulatory functions of exosomes in a tumor microenvironment in order to further understand the processes of tumorigenesis,progression,metastasis,drug resistance and immune escape.It can also be used as important markers for early diagnosis and prognosis evaluation of tumor patients.In this paper,the role of exosomes in tumor microenvironment will be introduced.

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