|Table of Contents|

Advances in research on lung cancer driving genes,detection and targeted therapy

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2020 02
Page:
330-334
Research Field:
Publishing date:

Info

Title:
Advances in research on lung cancer driving genes,detection and targeted therapy
Author(s):
Fan YipingDu MingYu FuyaoXiu Jun
Department of Radiology,Shengjing Hospital of China Medical University,Liaoning Shenyang 110004,China.
Keywords:
lung cancerdriver genetargeted therapy
PACS:
R734.2
DOI:
10.3969/j.issn.1672-4992.2020.02.035
Abstract:
Lung cancer is the most malignant tumors with the highest morbidity and mortality worldwide.Different types of lung cancer behave differently for specific genetic alterations that result in sustained expression of oncogene activation and signaling,and the definition of oncogenes by obtaining mutations can lead to a dominant gain in target protein function.A growing body of evidence supports that targeted cancer-causing pathways are not individual oncogenes but are determined by multiple genes.With the continuous development of genetic analysis and molecular diagnostic technology and the application of next-generation sequencing technology and the development of targeted drugs,it has improved the traditional treatment of lung cancer and brought new hope for the survival of lung cancer patients.

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Memo

Memo:
辽宁省教育厅重点实验室基础研究项目(编号: LZ2015079)
Last Update: 2019-11-29