|Table of Contents|

Short-term effect observation of total obstructive esophageal cancer treatment by nutritional support by peripherally inserted central venous catheter and intensity modulated radiation therapy

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2020 02
Page:
223-226
Research Field:
Publishing date:

Info

Title:
Short-term effect observation of total obstructive esophageal cancer treatment by nutritional support by peripherally inserted central venous catheter and intensity modulated radiation therapy
Author(s):
Zhao Hui; Zhu Chengbin; Zhang Heng; Zhang Jianqing
Radiotherapy Department,People's Hospital of Xinjiang Uygur Autonomous Region,Xinjiang Urumqi 830000,China.
Keywords:
central venous catheterization; nutrition; radiotherapy; complete obstruction; esophageal cancer
PACS:
R735.1
DOI:
10.3969/j.issn.1672-4992.2020.02.010
Abstract:
Objective:To investigate the short-term efficacy of peripherally implanted central venous catheter (PICC) nutrition plus three-dimensional conformal intensity modulated radiation therapy for completely obstructive esophageal cancer.Methods:36 patients with esophageal squamous cell carcinoma and complete obstruction admitted to the People's Hospital of Xinjiang Uygur Autonomous Region from May 2010 to October 2017 were selected the subjects.All patients received 1~2 weeks of peripherally implanted PICC total nutritional support therapy,followed by three-dimensional conformal intensity modulated radiation therapy.The target prescription dose was 95%PTV 60~66 Gy/30~33 f,2 Gy/f,5 times/week.The general situation,clinical benefit,improvement of eating symptoms,alleviation of obstruction and occurrence of acute adverse reactions were observed.Results:After treatment,the general condition of the patients improved significantly (P＜0.05).The clinical benefit response of patients was improved (P＜0.05).The clinical benefit rate was 100%,and the total effective rate of improving eating symptoms was 83.3%.The total effective rate of recent obstruction relief was 91.7%.The main acute adverse reactions of radiotherapy were mild tracheal reaction,leukopenia,thrombocytopenia and nausea,which were tolerable.Conclusion:Active PICC nutritional support plus three-dimensional conformal intensity modulated radiation therapy for patients with complete obstructive esophageal cancer can improve their physical quality,improve eating symptoms and alleviate esophageal obstruction,with less adverse reactions.

References:

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Memo

Memo:
新疆维吾尔自治区自然科学基金项目（编号:2014211A065）；新疆维吾尔自治区人民医院科技引进创新项目（编号:20180209）
Last Update: 2019-11-29