|Table of Contents|

The progress of pulmonary large cell neuroendocrine carcinoma' s diagnosis and treatment

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2020 01
Page:
169-173
Research Field:
Publishing date:

Info

Title:
The progress of pulmonary large cell neuroendocrine carcinoma' s diagnosis and treatment
Author(s):
Fan MingmingZhang Jie
Department of Respiratory and Critical Care Medicine,the Second Hospital of Jilin University,Jilin Changchun 130041,China.
Keywords:
pulmonary large cell neuroendocrine carcinomadiagnosistreatment
PACS:
R734.2
DOI:
10.3969/j.issn.1672-4992.2020.01.040
Abstract:
Pulmonary large cell neuroendocrine carcinoma(LCNEC)is a malignancy with aggressive behavior and poor prognosis,is classified as neuroendocrine carcinoma,occurs more frequently in heavy and elderly male smokers.A growing evidence suggests that LCNEC is a kind of genetics,histology,biological highly heterogeneous group.The treatment of LCNEC often takes example by small cell lung carcinoma(SCLC)or non-small cell lung carcinoma(NSCLC).For early stage LCNEC,surgery is recommeded,and platinum-based adjuvant chemotherapy can be used after resection.For advanced stage LCNEC,chemotherapy is controversial,and targeted therapy,immune therapy,radiation and so on are in exploration.This paper summarizes the current situation and research progress of clinical diagnosis and treatment in related fields.

References:

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