[1]Ettinger DS,Aisner DL,Wood DE,et al.NCCN guidelines insights:Non-small cell lung cancer,version 5.2018[J].J Natl Compr Canc Netw,2018,16(7):807-821.
[2]Ettinger DS,Wood DE,Akerley W,et al.Non-small cell lung cancer,version 6.2015[J].J Natl Compr Canc Netw,2015,13(5):515-524.
[3]Ponting CP,Belgard TG.Transcribed dark matter:Meaning or myth[J]? Hum Mol Genet,2010,19(R2):R162-168.
[4]Herceg Z.Epigenetic information in chromatin and cancer[J].Eur J Cancer,2009,45(Suppl 1):442-444.
[5]Mitra SA,Mitra AP,Triche TJ.A central role for long non-coding RNA in cancer[J].Front Genet,2012(3):17.
[6]Zhang J,Yin M,Huang J,et al.Long noncoding RNA LINC00152 as a novel predictor of lymph node metastasis and survival in human cancer:A systematic review and meta-analysis[J].Clin Chim Acta,2018(483):25-32.
[7]Okazaki Y,Furuno M,Kasukawa T,et al.Analysis of the mouse transcriptome based on functional annotation of 60 770 full-length cDNAs[J].Nature,2002,420(6915):563-573.
[8]Guttman M,Amit I,Garber M,et al.Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals[J].Nature,2009,458(7235):223-227.
[9]Hauptman N,Glavac D.Long non-coding RNA in cancer[J].Int J Mol Sci,2013,14(3):4655-4669.
[10]Malek E,Jagannathan S,Driscoll JJ.Correlation of long non-coding RNA expression with metastasis,drug resistance and clinical outcome in cancer[J].Oncotarget,2014,5(18):8027-8038.
[11]Bernard D,Prasanth KV,Tripathi V,et al.A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression[J].EMBO J,2010,29(18):3082-3093.
[12]Tripathi V,Ellis JD,Shen Z,et al.The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation[J].Mol Cell,2010,39(6):925-938.
[13]Gutschner T,Hmmerle M,Eissmann M,et al.The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells[J].Cancer Res,2013,73(3):1180-1189.
[14]Xu YJ,Du Y,Fan Y.Long noncoding RNAs in lung cancer:What we know in 2015[J].Clin Transl Oncol,2016,18(7):660-665.
[15]Rinn JL,Kertesz M,Wang JK,et al.Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs[J].Cell,2007,129(7):1311-1323.
[16]Gupta RA,Shah N,Wang KC,et al.Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis[J].Nature,2010,464(7291):1071-1076.
[17]Ling H,Spizzo R,Atlasi Y,et al.CCAT2,a novel noncoding RNA mapping to 8q24,underlies metastatic progression and chromosomal instability in colon cancer[J].Genome Res,2013,23(9):1446-1461.
[18]Zhang X,Chen Q,He C,et al.Polymorphisms on 8q24 are associated with lung cancer risk and survival in Han Chinese[J].PLoS One,2012,7(7):e41930.
[19]Hou Z,Zhao W,Zhou J,et al.A long noncoding RNA Sox2ot regulates lung cancer cell proliferation and is a prognostic indicator of poor survival[J].Int J Biochem Cell Biol,2014(53):380-388.
[20]Guan Y,Kuo WL,Stilwell JL,et al.Amplification of PVT1 contributes to the pathophysiology of ovarian and breast cancer[J].Clin Cancer Res,2007,13(19):5745-5755.
[21]Takahashi Y,Sawada G,Kurashige J,et al.Amplification of PVT-1 is involved in poor prognosis via apoptosis inhibition in colorectal cancers[J].Br J Cancer,2014,110(1):164-171.
[22]Cui D,Yu CH,Liu M,et al.Long non-coding RNA PVT1 as a novel biomarker for diagnosis and prognosis of non-small cell lung cancer[J].Tumour Biol,2016,37(3):4127-4134.
[23]Han L,Zhang EB,Yin DD,et al.Low expression of long noncoding RNA PANDAR predicts a poor prognosis of non-small cell lung cancer and affects cell apoptosis by regulating Bcl-2[J].Cell Death Dis,2015(6):e1665.
[24]Shi Y,Li J,Liu Y,et al.The long noncoding RNA SPRY4-IT1 increases the proliferation of human breast cancer cells by upregulating ZNF703 expression[J].Mol Cancer,2015(14):51.
[25]Khaitan D,Dinger ME,Mazar J,et al.The melanoma-upregulated long noncoding RNA SPRY4-IT1 modulates apoptosis and invasion[J].Cancer Res,2011,71(11):3852-3862.
[26]MAO PY,SUN M,SHEN D,et al.The impact of long noncoding RNA SPRY4-IT1 in proliferation and invasion of non-small-cell-lung cancer[J].Modern Oncology,2017,25(07):1006-1010.[茅佩瑶,孙明,沈冬,等.长链非编码RNA SPRY4-IT1对非小细胞肺癌细胞增殖和侵袭的影响及机制[J].现代肿瘤医学,2017,25(07):1006-1010.]
[27]Sun J,Li W,Sun Y,et al.A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies[J].Nucleic Acids Res,2014,42(15):9588-9601.
[28]Fürstenberger G,Senn HJ.Insulin-like growth factors and cancer[J].Lancet Oncol,2002,3(5):298-302.
[29]Reinmuth N,Liu W,Fan F,et al.Blockade of insulin-like growth factor I receptor function inhibits growth and angiogenesis of colon cancer[J].Clin Cancer Res,2002,8(10):3259-3269.
[30]Li N,Feng XB,Tan Q,et al.Identification of circulating long noncoding RNA Linc00152 as a novel biomarker for diagnosis and monitoring of non-small-cell lung cancer[J].Dis Markers,2017(2017):7439698.
[31]Sun M,Liu XH,Wang KM,et al.Downregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial-mesenchymal transition[J].Mol Cancer,2014(13):68.
[32]Liu Z,Sun M,Lu K,et al.The long noncoding RNA HOTAIR contributes to cisplatin resistance of human lung adenocarcinoma cells via downregualtion of p21(WAF1/CIP1)expression[J].PLoS One,2013,8(10):e77293.
[33]Akers JC,Gonda D,Kim R,et al.Biogenesis of extracellular vesicles(EV):Exosomes,microvesicles,retrovirus-like vesicles,and apoptotic bodies[J].J Neurooncol,2013,113(1):1-11.
[34]Shi T,Gao G,Cao Y.Long Noncoding RNAs as novel biomarkers have a promising future in cancer diagnostics[J].Dis Markers,2016(2016):9085195.