|Table of Contents|

Progress in research on epithelial-mesenchymal transition in cervical cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2020 01
Page:
142-148
Research Field:
Publishing date:

Info

Title:
Progress in research on epithelial-mesenchymal transition in cervical cancer
Author(s):
Liu XiaominWang Ning
The Third Gynecological Reproductive Endocrinology Ward,Shengjing Hospital of China Medical University,Liaoning Shenyang 110000,China.
Keywords:
cervical cancerepithelial-mesenchymal transitionmicroRNAinvasion and metastasis
PACS:
R737.33
DOI:
10.3969/j.issn.1672-4992.2020.01.034
Abstract:
Cervical cancer is one of the most common gynecological malignancies,which is a serious threat to women's health,and the incidence has become younger in recent years.Despite the use of advanced screening methods and preventive vaccines,more than half of cervical cancer cases are diagnosed as advanced stage in the case of extremely limited treatment options and severe side effects.How to solve the above problems requires a better understanding of cervical cancer from the molecular biology level.Among them,epithelial-mesenchymal transition(EMT)is a hotspot in recent years.EMT is a reversible biological process from epithelial cell phenotype to mesenchymal cell phenotype.EMT can promote the migration and invasion of cervical cancer cells,and then promote metastasis of tumors.The shift affects the patient's prognosis.This article summarizes the current researches progress and will review the progress of EMT related research on cervical cancer in recent years.

References:

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Memo

Memo:
National Natural Science Foundation of China(No.81202047);国家自然科学基金青年项目(编号:81202047)
Last Update: 1900-01-01