|Table of Contents|

Analysis of related factors of axillary lymph node metastasis in male breast cancer patients based on SEER database

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2020 01
Page:
66-69
Research Field:
Publishing date:

Info

Title:
Analysis of related factors of axillary lymph node metastasis in male breast cancer patients based on SEER database
Author(s):
Yang Hongwei1; Chen Maoshan1; Yang Guanglun2; Huang Yunhui1; Hou Lingmi3; Liu Ying1
1.Department of Breast and Thyroid Surgery，Suining Central Hospital，Sichuan Suining 629000，China；2.Department of Endocrine and Breast Surgery，the First Affiliated Hospital of Chongqing Medical University，Chongqing 400016，China；3.Department of Breast and Thyroid Surgery，Affiliated Hospital of North Sichuan Medical College，Sichuan Nanchong 637000，China.
Keywords:
breast cancer; lymph node status; related factor; SEER database
PACS:
R737.9
DOI:
10.3969/j.issn.1672-4992.2020.01.016
Abstract:
Objective：To analyze the related factors of axillary lymph node(ALN)metastases in male patients with breast cancer.Methods：1 636 patients with male breast cancer(MBC)were extracted from the Surveillance，Epidemiology，and End Results (SEER) database diagnosed between 2010 and 2014 years.The association between ALN status and clinicopathological features were retrospectively analysed.Results：The ALN metastatic rate of all enrolled population was 45.17%.The ALN status was significantly associated with the tumor site(P=0.001)，grade(P<0.001)，tumor size(P<0.001) and human epidermal growth factor-2 (HER-2)(P=0.015) in the univariate analysis.But there was no significant difference with the age(P=0.295)，estrogen receptor(P=0.725)and progestogen receptor(P=0.848).In binary logistic analysis，tumor site（OR=1.368，95%CI 1.083~1.723，P=0.009），grade (OR=1.241，95%CI 1.029~1.497，P=0.024) and tumor size(OR=1.041，95%CI 1.029~1.052，P<0.001) were independent predictors for ALN metastasis in MBC.However，HER-2 status(OR=1.150，95%CI 0.800~1.653，P=0.449) was not the independent predictor for ALN status.Conclusion：Tumor size，tumor site and histological grade were the independent predictors for ALN metastasis in MBC.

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