|Table of Contents|

Monitoring of circulating tumor cells in patients with metastatic colorectal cancer undergoing microwave ablation

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2019 06
Page:
1005-1008
Research Field:
Publishing date:

Info

Title:
Monitoring of circulating tumor cells in patients with metastatic colorectal cancer undergoing microwave ablation
Author(s):
Jiang Wen1; Wang Lixue1; Ding Huaiyin1; Zheng Qin1; Yang Mi2; Zhang Quanan3; Xu Hanfeng1
1.The Second Hospital Attached to Southeast University,Jiangsu Nanjing 210003,China;2.Cancer Center，Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School，Clinical Cancer Institute of Nanjing University，Jiangsu Nanjing 210008,China;3.Department of Oncology，the Affiliated Jiangning Hospital of Nanjing Medical University,Jiangsu Nanjing 211100,China.
Keywords:
metastatic colorectal cancer; circulating tumor cell; microwave ablation
PACS:
R735.3
DOI:
10.3969/j.issn.1672-4992.2019.06.025
Abstract:
Objective:To investigate the clinical value of circulating tumor cells (CTCs) in evaluating the prognostic value in patients with metastatic colorectal cancer undergoing microwave ablation.Methods:Total of 34 patients who received microwave ablation for hepatic or pulmonary metastases from colorectal cancer at the Second Hospital Attached to Southeast University from January 2015 to April 2018 were enrolled in this study.Preoperative blood samples from these patients were tested for CTCs.CTCs values and clinical materials of the 34 cases were analysed.Results:An increase in CTCs values after microwave ablation was found (P=0.003).There were significant differences in prognosis between CTCs values ≥7/ml and ＜7/ml after microwave ablation (P=0.030) and in gender （P=0.011）.However,age,site of microwave ablation and the change of CTC values after microwave ablation were no statistically significant (P＞0.05).Conclusion:The microwave ablation can cause the increase of CTCs values in the peripheral blood.There were significant differences in prognosis between CTCs values ≥7/ml and ＜7/ml after microwave ablation and in gender.

References:

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Memo

Memo:
中国肝炎防治基金会-天晴肝病研究基金资助课题（编号：TQGB20150170）;江苏省卫计委面上科研课题基金资助项目（编号：H201648）
Last Update: 1900-01-01