|Table of Contents|

Research progress of circulating tumor DNA in non-small cell lung cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2019 05
Page:
889-902
Research Field:
Publishing date:

Info

Title:
Research progress of circulating tumor DNA in non-small cell lung cancer
Author(s):
Xu Fu
People's Liberation Army No.202 Hospital,Liaoning Shenyang 110003,China.
Keywords:
circulating tumor DNAnon-small cell lung cancerliquid biopsyprecision medicine
PACS:
R730.4
DOI:
10.3969/j.issn.1672-4992.2019.05.046
Abstract:
Targeted therapy and immunotherapy for non-small cell lung cancer(NSCLC) depend on molecular typing,but the detection of sensitive genes and drug resistance genes is difficult and invasive due to the difficulty in obtaining biopsy specimens.Circulating tumor DNA(ctDNA),as a non-invasive "liquid biopsy" method,has shown promising application prospects as detection technology advances.This article will review the research and application of ctDNA technology in the diagnosis of non-small cell lung cancer,targeted drug efficacy prediction and drug resistance monitoring.

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Last Update: 2019-02-01