|Table of Contents|

Clinical value of PET/CT imaging in the recurrence and metastasis of gynecologic malignant tumors postoperatively

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2019 04
Page:
657-660
Research Field:
Publishing date:

Info

Title:
Clinical value of PET/CT imaging in the recurrence and metastasis of gynecologic malignant tumors postoperatively
Author(s):
Chen Lanlan; Hao Shanhu; Zhang Guoxu; Wu Xiaodan; Zhan Ying
Department of Nuclear Medicine,The General Hospital of Shenyang Military Command,Liaoning Shenyang 110016,China.
Keywords:
gynecologic genital tumor; recurrence; tumor metastasis; tomography emission-computed; tomography X-ray computed; positron emission tomography; deoxyglucose
PACS:
R737.3
DOI:
10.3969/j.issn.1672-4992.2019.04.029
Abstract:
Objective:To investigate the clinical value of positron emission tomography (PET/CT) in the recurrence and metastasis of gynecologic malignant tumors.Methods:We analyzed retrospectively the imaging results of 56 patients with postoperative gynecological malignant tumors who underwent PET/CT in our center from January 2015 to December 2016.The diagnosis was evaluated by postoperative pathological results,the elevated level of blood glucose anti-tumor antigen 125 (CA125) and the clinical follow-up results.The diagnostic efficacy of PET/CT on the recurrence and metastasis of gynecological malignant tumor was evaluated.Results:In 56 patients,the pathological results,the continuous elevation of serum CA125 level and clinical follow-up results confirmed that 25 cases of tumor recurrence and metastasis,26 cases of metastasis without recurrence,3 cases of false positive,2 false negative cases.The specificity,sensitivity and accuracy of PET/CT imaging in gynecological malignant tumor recurrence and metastasis were 92.6%(25/27),89.7%(26/29),91.1%(51/56),respectively.Lesions were divided into vaginal stump,systemic lymph node and distant metastasis,the sensitivity and specificity of the PET/CT imaging of each metastasis were 87.5%(7/8) and 97.9%(47/48),95.0%(19/20) and 91.7%(33/36),91.3%(21/23) and 90.9%(30/33).PET/CT imaging showed that 6 patients have multiple sites and organ metastasis of the whole body,changed the clinical staging and treatment plan.Conclusion:PET/CT imaging has high sensitivity and specificity for metastasis and recurrence of gynecologic malignancies postoperatively.It has great guideline for the clinical stage and the treatment plan of postoperative recurrence and metastasis of gynecologic malignancies.

References:

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