|Table of Contents|

Research and progress of lncRNA ZFAS1 in tumor

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2019 03
Page:
537-540
Research Field:
Publishing date:

Info

Title:
Research and progress of lncRNA ZFAS1 in tumor
Author(s):
Wang Xiaoqiong1Cai Zhiyi12
1.The First Clinical Medical Institute of Wenzhou Medical College,Zhejiang Wenzhou 325000,China;2.Department of Otorhinolaryngology,Taizhou Municipal Hospital,Zhejiang Taizhou 318000,China.
Keywords:
tumorlong non-coding RNAZFAS1molecular mechanism
PACS:
R730.231
DOI:
10.3969/j.issn.1672-4992.2019.03.044
Abstract:
Long non-coding RNAs(lncRNAs) are a class of RNA molecules longer than 200 nucleotides.ZFAS1 is a newly identifed lncRNA,which expresses differently in kinds of tumors,such as breast cancer,lung cancer,liver cancer,and gastric cancer.Further studies have found that the function of ZFAS1 is complex and can play the role as carcinogen or tumor suppressor by different ways in different tumors.For example,it is thought have the ability to promote epithelial-mesenchymal transition(EMT) process,stimulate cell proliferation,inhibit apoptosis.This article is a brief overview of the development and role of ZFAS1 in different malignant tumors,combined with the latest reports at home and abroad.

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Last Update: 2018-12-29