|Table of Contents|

Progress in the treatment of extensive-stage small cell lung cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2019 02
Page:
359-362
Research Field:
Publishing date:

Info

Title:
Progress in the treatment of extensive-stage small cell lung cancer
Author(s):
Ren XiaoxuMa Rui
Department of Thoracic Medicine Ⅱ Ward,Cancer Hospital of China Medical University,Liaoning Cancer Hospital & Institute,Liaoning Shenyang 110042,China.
Keywords:
small cell lung cancerextensive stagechemotherapymolecular targeted therapyimmune checkpoint inhibitors
PACS:
R734.2
DOI:
10.3969/j.issn.1672-4992.2019.02.046
Abstract:
Extensive-stage small cell lung cancer (SCLC) remains a disease with a dismal prognosis,with median survival of approximately 8~10 months.There was not any breakthrough in the treatment of SCLC,and two platinum treatment options have been the first choice.Virtually all patients develop relapse or resistance,for those only have few therapy unluckily,so the existing treatment has reached the bottleneck.With a new understanding of molecular biology behavior,research has shifted to molecular targeting and immunotherapy.With the advent of a large number of experimental drugs,the development of new drugs has been promoted.The performance of a series of drugs in early clinical trials seems to have broken the curse that "small cell lung cancer is the tomb of drug development".These new drugs mainly include anti-angiogenesis inhibitors,immune checkpoint inhibitors,anti-apoptotic protein inhibitors,anti-drug drugs and so on.We are looking forward to a glimmer of hope for the treatment of patients with extensive-stage small cell lung cancer.

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Last Update: 1900-01-01