|Table of Contents|

Research progress of circulating tumor DNA in recurrent and metastatic breast cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2019 02
Page:
339-342
Research Field:
Publishing date:

Info

Title:
Research progress of circulating tumor DNA in recurrent and metastatic breast cancer
Author(s):
Yang YunHuang Yuanxi
Department of Breast Surgery,Harbin Medical University Cancer Hospital,Heilongjiang Harbin 150086,China.
Keywords:
recurrent metastatic breast cancerctDNAearly diagnosisexploration of drug resistanceprognosis
PACS:
R737.9
DOI:
10.3969/j.issn.1672-4992.2019.02.041
Abstract:
With the development of the medical technology,concept of precision medical treatment proposed,considerable attention has been paid to the utility of circulating tumor DNA (ctDNA) detection in cancer.ctDNA carries the same genetic information of the tumor and reacts with the tumor load.It is used for early cancer screening,drug resistance,recurrence and metastasis,and prognosis evaluation.In this paper,we will further explore the role of circulating tumor DNA in recurrent and metastatic breast cancer,making it a routine detection index for monitoring metastasis and prognosis in breast cancer patients,and help to clarify drug resistance,and find a new target for breast cancer metastasis therapy.

References:

[1]Anderson GL,Barrington WE.Narrowing of racial disparities in breast cancer incidence:Insights from menopausal hormone therapy study findings[J].J Natl Cancer Inst,2016,108(4):djv393.
[2]Qiu SQ,Zeng HC,Zhang F,et al.A nomogram to predict the probability of axillary lymph node metastasis in early breast cancer patients with positive axillary ultrasound[J].Sci Rep,2016,6:21196.
[3]Schwarzenbach H,Pantel K.Circulating DNA as biomarker in breast cancer[J].Breast Cancer Research,2015,17(1):136.
[4]Hampton T.Circulating tumor DNA helps track cancer[J].Journal of the American Medical Association,2016,315:19.
[5]Peter U,Martina A,Ellen H.Detection of circulating tumor DNA in the blood of cancer patients:An important tool in cancer chemoprevention[J].Methods in Molecular Biology,2016,1379:45-68.
[6]Lianos GD,Mangano A,Cho WC,et al.Circulating tumor DNA:new horizons for improving cancer treatment[J].Future Oncology,2015,11(4):545-548.
[7]Ryder CB,Schmotzer CL.Circulating tumor DNA:The future of personalized medicine in oncology[J]?Clinical Chemistry,2015,61(2):443.
[8]Gold B,Cankovic M,Furtado LV,et al.Do circulating tumor cells,exosomes,and circulating tumor nucleic acids have clinical utility?A report of the association for molecular pathology[J].Journal of Molecular Diagnostics,2015,17(3):209-224.
[9]Mouliere F,Rosenfeld N.Circulating tumor-derived DNA is shorter than somatic DNA in plasma[J].Proceedings of the National Academy of Sciences of the United States of America,2015,112(11):3178.
[10]Chetan Bettegowda,Mark Sausen,Rebecca Leary,et al.Detection of circulating tumor DNA in early and late stage human malignancies[J].Science Translational Medicine,2014,6(224):224ra24.
[11]Ondrouková E,Hrstka R.Circulating tumor DNA in blood and its utilization as a potential biomarker for cancer[J].Klin Onkol,2015,28(Suppl 2):69-74.
[12]García-Casas A,García-Olmo DC,García-Olmo D.Further the liquid biopsy:Gathering pieces of the puzzle of genometastasis theory[J].World Journal of Clinical Oncology,2017,8(5):378.
[13]Saliou A,Bidard FC,Lantz O,et al.Circulating tumor DNA for triple-negative breast cancer diagnosis and treatment decisions[J].Expert Rev Mol Diagn,2016,16(1):39-50.
[14]Caen O,Nizard P,Garrigou S,et al.Digital PCR compartmentalization II.Contribution for the quantitative detection of circulating tumor DNA[J].Med Sci,2015,31(2):180-186.
[15]Carpinetti P,Donnard E,Bettoni F,et al.The use of personalized biomarkers and liquid biopsies to monitor treatment response and disease recurrence in locally advanced rectal cancer after neoadjuvant chemoradiation[J].Oncotarget,2015,6(35):38360-38371.
[16]Benard A,van de Velde CJ,Lessard L,et al.Epigenetic status of LINE-1 predicts clinical outcome in early-stage rectal cancer[J].British Journal of Cancer,2013,109(12):3073-3083.
[17]Taniguchi K,Uchida J,Nishino K,et al.Quantitative detection of EGFR mutations in circulating tumor DNA derived from lung adenocarcinomas[J].Clinical Cancer Research,2011,17(24):7808-7815.
[18]Vallée A,Audigier-Valette C,Herbreteau G,et al.Rapid clearance of circulating tumor DNA during treatment with AZD9291 of a lung cancer patient presenting the resistance EGFR T790M mutation[J].Lung Cancer,2015,91(2):73-74.
[19]Wise JE.(S036) Circulating tumor DNA and implications for clinical decision-making in stage I NSCLC[J].Oncology,2015,29(4 Suppl 1):628-639.
[20]Goto T,Hirotsu Y,Oyama T,et al.Analysis of tumor-derived DNA in plasma and bone marrow fluid in lung cancer patients[J].Medical Oncology,2016,33(3):29.
[21]Yrüker EE,zgür E,Keskin M,et al.Assessment of circulating serum DNA integrity in colorectal cancer patients[J].Anticancer Research,2015,35(4):2435-2440.
[22]Tanaka T,Sakano A.Correlation of BRAF mutation status in circulating-free DNA and tumor and association with clinical outcome across four BRAFi and MEKi clinical trials[C].Clin Cancer Res,2016:2771-2777.
[23]Bear HD,Tang G,Rastogi P,et al.Neoadjuvant plus adjuvant bevacizumab in early breast cancer(NSABP B-40 [NRG Oncology]):Secondary outcomes of a phase 3,randomised controlled trial[J].Lancet Oncol,2015,16(9):1037-1048.
[24]Payandeh M,Sadeghi M,Sadeghi E.Differences in prognostic factors between early and late recurrence breast cancers[J].Asian Pac J Cancer Prev,2015,16(15):6575-6579.
[25]Garcia-Murillas I,Schiavon G,Weigelt B,et al.Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer[J].Sci Transl Med,2015,7(302):302ra133.
[26]Schiavon G,Hrebien S,Garciamurillas I,et al.Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer[J].Science Translational Medicine,2015,7(313):313ra182.
[27]Rothé F,Laes JF,Lambrechts D,et al.Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analysis in breast cancer[J].Annals of Oncology,2014,25(10):1959.
[28]Murtaza M,Dawson SJ,Tsui DW,et al.Non- invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA[J].Nature,2013,497(7447):108-112.
[29]Nagalingam A,Tighiouart M,Ryden L,et al.Med1 plays a critical role in the development of tamoxifen resistance[J].Carcinogenesis,2012,33(4):918-930.
[30]Li F,Song ZJ,Wang CT,et al.Optimization of maintenance therapy for advanced breast cancer and analysis of clinical application of circulating tumor DNA[J].Clinical Research and Practice,2017,2(24):09-10.[李飞,宋张骏,汪存涛,等.晚期乳腺癌维持治疗的优化及循环肿瘤DNA在临床的应用分析[J].临床医学研究与实践,2017,2(24):09-10.]
[31]Dawson SJ,Tsui DW,Murtaza M,et al.Analysis of circulating tumorDNA to monitor metastatic breast cancer[J].N Engl J Med,2013,368(13):1199-1209.
[32]Hamakawa T,Kukita Y,Kurokawa Y,et al.Monitoring gastric cancer progression with circulating tumour DNA[J].Br J Cancer,2015,112:352-356.
[33]Ma M,Zhu H,Zhang C,et al."Liquid biopsy"-ctDNA detection with great potential and challenges[J].Annals of Translational Medicine,2015,3(16):235.

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