|Table of Contents|

Comparison of oxycodone hydrochloride and dezocine preemptive analgesia for upper abdominal operation

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2016 06
Page:
968-970
Research Field:
Publishing date:

Info

Title:
Comparison of oxycodone hydrochloride and dezocine preemptive analgesia for upper abdominal operation
Author(s):
Zhao Wenhui1Chen Jun1Jing Guixia2
1.Department of Anesthesiology,Shaanxi Provincial Tumor Hospital,Shaanxi Xi'an 710061,China;2.Department of Anesthesiology,the First Affiliated Hospital,Medical School of Xi'an Jiaotong University,Shaanxi Xi'an 710061,China.
Keywords:
oxycodonedezocineanalgesia in advanceupper abdominal surgery
PACS:
R730.59
DOI:
10.3969/j.issn.1672-4992.2016.06.036
Abstract:
Objective:To evaluate the clinical efficacy and safety of oxycodone in preemptive analgesia for upper abdominal surgery.Methods:Selecting eighty patients with upper abdominal surger randomly dividing them into two groups:Oxycodone group (Group O,n=40) and dezocine group(Group D,n=40).30 minutes before the surgery,group O(n=40) was injected with oxycodone (0.01mg/kg,iv),and group D(n=40) injected dezocine (0.01mg/kg,iv).To observe hemodynamic index during recovery,recovery time,extubation time,VAS,and BCS.Emergence agitation and adverse events such as respiratory depression,nausea and vomiting,drowsiness,and pruritus were assessed.Results:The changes of MAP and HR,recovery time,and the incidence of emergence agitation showed no significant difference between the two groups(P>0.05).Group O T1(extubation),T2(extubation 5 min),T3(extubation 15 min),T4(extubation 30 min) point of VAS score were lower than that of group D(P<0.05),BCS score higher than that of group D(P<0.05),drowsiness rate was lower than that of group D.The incidence of nausea and vomiting showed no significant difference between the two groups.There was no respiratory depression in two groups.Conclusion:Compared with morphine,oxycodone hydrochloride injection,with less adverse effects,has no influence on analepsia of patients with upper abdominal surgery and can effectively relieve pain.

References:

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Last Update: 2016-01-29