|Table of Contents|

Effects of Cinobufotalin on the growth of cervical cancer cell

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2015 13
Page:
1802-1804
Research Field:
Publishing date:

Info

Title:
Effects of Cinobufotalin on the growth of cervical cancer cell
Author(s):
Huang Meihua1; Zhu Chenyu2; Shang Yuanfang2
1.Department of Gynecology，The Central Hospital of Enshi Autonomous Prefecture，Hubei Enshi 445000，China；2.The First College of Clinical Medical Science，China Three Gorges University，Hubei Yichang 443000，China.
Keywords:
Cinobufotalin; cervical cancer cell lines HeLa; cell proliferation
PACS:
R73-3；R737.33
DOI:
10.3969/j.issn.1672-4992.2015.13.06
Abstract:
Objective：To explore the effects of Cinobufotalin on the growth of cervical cancer cell lines HeLa.Methods：The inhibitory effect of Cinobufotalin on cell proliferation was examined by MTT assay and cell cycle was detected by flow cytometry (FCM).Wound healing test was used to measure the migration ability of HeLa cells.Results：Cinobufotalin singnificantly inhibited cell proliferation，blocked the cell cycle in the G0/G1 phase.The migration capacity of Cinobufotalin-treated cells was decreased compared with that of the negative control cells.Conclusion：Cinobufotalin singnificantly inhibited cell proliferation，blocked the cell cycle in the G0/G1 phase，and decreased the migration ability of HeLa cells significantly.

References:

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Last Update: 2015-05-29